Protein Alignment LysRS and dars1

DIOPT Version :9

• Sequence 1: NP_001188571.1
• Gene: LysRS / 31904
• FlyBaseID: FBgn0027084
• Length: 607
• Species: Drosophila melanogaster
• Sequence 2: NP_989306.1
• Gene: dars1 / 394926
• XenbaseID: XB-GENE-951509
• Length: 531
• Species: Xenopus tropicalis
• Alignment Length: 587
• Identity: 138/587 - (23%)
• Similarity: 241/587 - (41%)
• Gaps: 112/587 - (19%)

  Fly    37 EPSKQTKLELKRRLKAEQKAKEKAEKAAAAPAENTAGKKKSSAAEEEEISPNEYFKLRSAAVQEL 101
            |...|:|..||::.|..:||.:||||.|...:|        ..|||||    ::.|.|......:
 Frog    13 EEQAQSKKALKKQQKEAEKAAKKAEKQAKLASE--------QQAEEEE----DFAKERYGVPSMI 65

  Fly   102 KRSPATDPYPHKFHVSSSLEDFIAKYENSLKEGETLENVKLSVAGRVHAIRESGAKLIFYDLRGE 166
            :.....|      .|...::|...:     |..||     :.|..|||..|..| |..|..||.:
 Frog    66 QSQEKPD------RVLVRVKDLTVQ-----KADET-----VWVRARVHTSRAKG-KQCFLVLRQQ 113

  Fly   167 GVKVQVMASA--KSYKSEADFEIDTSKLRRGDIIGVVGHPGKTKKGELSVMPSEIKLLSPCLHML 229
            ...||.:.:.  ::.|....|..:.:|....|:.|||   .|..:...|....:::|....::::
 Frog   114 QFNVQALVAVGERASKQMVKFAANITKESIVDVEGVV---RKVDQKIESCTQQDVELHIERIYVI 175

  Fly   230 ----PHLHFGLKD-----------------KETRYRQRYLDLILNNNVREKFQIRAKIISYVRQF 273
                |.|...|:|                 ::||...|.:||..:.: :..|.:::.:....|:.
 Frog   176 SAAEPRLPLQLEDAVRPETEGDEEGRATVNQDTRLDNRVIDLRTSTS-QAVFGLQSGVCQLFRET 239

  Fly   274 LDRLGFLEIETPMMNMIAGGATAKPFVTHHNDLKMDLFMRIAPELYHKMLVVGGLDRVYEIGRQF 338
            |.:.||:||:||.:...|....|..|...:  .|...::..:|:||.:|.:....::|:.||..|
 Frog   240 LTQKGFVEIQTPKIISAASEGGANVFTVSY--FKTSAYLAQSPQLYKQMCICADFEKVFCIGPVF 302

  Fly   339 RNEGIDL-THNPEFTTCEFYMAY-ADYADIMD-ITEQLVSGMVKAIRGSYKVIYHPEGPEGPEQE 400
            |.|..:. .|..||...:..||: ..|.:::| |.:.||. :.|.::..::........:.|.:.
 Frog   303 RAEDSNTHRHLTEFVGLDIEMAFNYHYHEVVDEIADTLVQ-IFKGLQERFQTEIQTVCKQFPSEP 366

  Fly   401 LDFTPPFKR------VSMIKTLEEKLQVKFPAADTFNSPETNQFLSQLCAKHQVECPAPRTTARL 459
            ..|..|..|      |:|::    :..|:....:..::|  |:.|.....|.:.:     |...:
 Frog   367 FKFLEPTLRLEYTEGVAMLR----EAGVEMGDEEDLSTP--NEKLLGRLVKEKYD-----TDFYI 420

  Fly   460 LDKLVGEFIEEFCVNPTFICEHPQIMSPLAKYHRSIPGLTERFELFVAKKEICNAYTELNDPVVQ 524
            |||.      ...|.|.:....||  .|  ||..|       :::|:..:||.:....::||.:.
 Frog   421 LDKY------PLAVRPFYTMPDPQ--DP--KYSNS-------YDMFMRGEEILSGAQRVHDPQLL 468

  Fly   525 RERFEQQASD----KAAGDDEAQLVDENFCTSLEYGLPPTGGFGMGIDRLAMFLTDSNNIKEVLL 585
            .||....|.|    ||            :..|..:|.||..|.|:|::|:.|.....:|:::..:
 Frog   469 TERATHHAIDLEKIKA------------YIDSFRFGAPPHAGGGIGLERVTMLYLGLHNVRQTSM 521

  Fly   586 FP 587
            ||
 Frog   522 FP 523

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
LysRS	NP_001188571.1	PLN02502	42..593	CDD:215278	136/582 (23%)
		LysRS_N	141..250	CDD:239817	29/131 (22%)
		LysRS_core	253..591	CDD:238398	80/348 (23%)
dars1	NP_989306.1	PLN02850	9..531	CDD:215456	138/587 (24%)
		AspRS_cyto_N	89..188	CDD:239815	26/107 (24%)
		AsxRS_core	204..527	CDD:238399	85/364 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910