Protein Alignment LysRS and dars-2

DIOPT Version :9

• Sequence 1: NP_001188571.1
• Gene: LysRS / 31904
• FlyBaseID: FBgn0027084
• Length: 607
• Species: Drosophila melanogaster
• Sequence 2: NP_506019.2
• Gene: dars-2 / 3565124
• WormBaseID: WBGene00001095
• Length: 593
• Species: Caenorhabditis elegans
• Alignment Length: 600
• Identity: 123/600 - (20%)
• Similarity: 225/600 - (37%)
• Gaps: 161/600 - (26%)

  Fly   102 KRSPATDPYPHKFHVSSSLEDFIAKYENSLKEGETLENVKLSVAGRVHAIRESGAKLIFYDLRGE 166
            :|..:|..|..:.|:...|             ..:.:|.|:||.|.:...|...    |:.||..
 Worm    13 RRILSTSSYTVRTHICDEL-------------STSNKNEKVSVMGWLSHKRMDR----FFVLRDA 60

  Fly   167 GVKVQVMASA--------KSYKSEADFEIDTSKLRRGDIIGVVGHPGKTKKGELSVMPSEIKLLS 223
            ...||...||        |....|:...:|...:.|||     ....|.|.|::.:...|:.:|:
 Worm    61 YGSVQAKISASSKLQSLLKDIPYESVVRVDGIVVDRGD-----NRNSKMKTGDIEIDVEELTVLN 120

  Fly   224 PCLHMLPHLHFGLKDKETRYRQRYLDLILNNNVREKFQIRAKIISYVRQFL-DRLGFLEIETP-M 286
            .....:|.|.....::.||.:.||:|| .::.:::..::|::.:..||:|| ::.||:::||| :
 Worm   121 KATSNIPMLPDANANERTRLKYRYIDL-RSDKLQKSLRLRSEFVHNVRRFLVEKSGFVDVETPTL 184

  Fly   287 MNMIAGGAT--AKPFVTHHNDLKMDLFMRIAPELYHKMLVVGGLDRVYEIGRQFRNEGIDLTHNP 349
            .....|||.  ..|..:.:..|...|..  :|:.:.::|:||.:||.::|.|.:|:||......|
 Worm   185 FRRTPGGAAEFVVPAPSPNQGLAYSLPQ--SPQQFKQLLMVGAIDRYFQIARCYRDEGSKGDRQP 247

  Fly   350 EFTTCEFYMAYADYADIMDITEQLVSGMVKAIRGSYKVIYHPEG-----PEGPEQELDFTPPFKR 409
            |||..:..|::.....:|.:.|.::            :...||.     |:.|...:.::...:.
 Worm   248 EFTQVDVEMSFTTQNGVMQLIEDMI------------ISAWPESLNHIKPKSPFPRIPYSDAMRL 300

  Fly   410 VSMIKTLEEKLQVKFPAADTFNSPETNQFLSQ--------------------------------- 441
            ..:.|   ..:::.:...|..|  :..:||.:
 Worm   301 YGIDK---PDMRIPWQIDDVDN--DIFEFLQKDIDDDTWRSRILVCRGAGKTTISNSMKNEWKRL 360

  Fly   442 -----------LCAKHQVECPAPRTTARLLDK--LVGEFIEEFCVN------------------- 474
                       :|...|.....|....:|:|:  |:.|.:...|..
 Worm   361 IQMNENGKNFAICHPSQKRWFKPFDNQKLIDQFGLIDEDVLIVCWGNSEGVYWTLEVCGLRSKSN 425

  Fly   475 ---------PTFICEHPQIMS-------PLAK-----YHRSIPGLT----ERFELFVAKKEICNA 514
                     |.|..|..|::|       ||.|     |...|..|.    :.::|.:...|:...
 Worm   426 VTAHWIVDFPLFSFEEGQLVSTHHPFTAPLEKDIDILYSNDIDKLLQITGQHYDLVINGVEMGGG 490

  Fly   515 YTELNDPVVQRERFEQQASDKAAGDDEAQLVDENFCTSLEYGLPPTGGFGMGIDRLAMFLTDSNN 579
            ...:.:..:||...      |..|:...::  |:...:|.:|.||.|||.:|:||....||...|
 Worm   491 SIRIENSEIQRHVL------KVLGEPTDEM--EHLLNALSHGAPPHGGFALGLDRFVAMLTSDGN 547

  Fly   580 ----IKEVLLFPAMK 590
                :::|:.||..|
 Worm   548 PLTPVRDVIAFPKTK 562

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
LysRS	NP_001188571.1	PLN02502	42..593	CDD:215278	122/599 (20%)
		LysRS_N	141..250	CDD:239817	29/116 (25%)
		LysRS_core	253..591	CDD:238398	85/440 (19%)
dars-2	NP_506019.2	aspS	24..591	CDD:234775	119/588 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910