Protein Alignment LysRS and AspRS-m

DIOPT Version :9

• Sequence 1: NP_001188571.1
• Gene: LysRS / 31904
• FlyBaseID: FBgn0027084
• Length: 607
• Species: Drosophila melanogaster
• Sequence 2: NP_001260520.2
• Gene: AspRS-m / 326155
• FlyBaseID: FBgn0051739
• Length: 1139
• Species: Drosophila melanogaster
• Alignment Length: 671
• Identity: 143/671 - (21%)
• Similarity: 252/671 - (37%)
• Gaps: 192/671 - (28%)

  Fly    55 KAKEK----------AEKAAAAPAENTAGKKKSSAAEEEEISPNEYFKLRSAAVQELKRSPA-TD 108
            |||||          ||:|||..:.|.......|..:..|.|..    ..::.:.|.:...| |:
  Fly   397 KAKEKKQKFSIDDLEAEEAAAEASANLTSNNGESTEDSAEASTT----ANASLIAEQRAKVADTN 457

  Fly   109 PYPHKFHVSSSLEDFIAKYENSLKEGETLENVKLSVAGRVHAIRESGAKLIFYDLRGEGVKVQVM 173
            .:..:.|....|.      .|.:.|       |:.:.|.:...|.:.    |:.||....:.||:
  Fly   458 KFADRTHNCGELT------SNDINE-------KVVICGWLEFQRMNK----FFILRDAYGQTQVL 505

  Fly   174 ASAKSYKSE--ADFEIDTSKLRRGDIIG-VVGHPG-----KTKKGELSVMPSEIKLLSPCLHMLP 230
            .|.|:|..|  |:..:....:.|  :.| |:..|.     |.:.|.:.|...::.:|:|....||
  Fly   506 LSPKTYGLEEYAETGVPIESIVR--VEGTVIPRPAATINPKMQTGHVEVEADKVVVLNPAKKNLP 568

  Fly   231 H--LHFGLKDKETRYRQRYLDLILNNNVREKFQIRAKIISYVRQFL-DRLGFLEIETP-MMNMIA 291
            .  ..|....:..|...|||||.. |:::...::|:.:|..:|::| :.|||:|:||| :.....
  Fly   569 FEIRKFNRAGERLRLTHRYLDLRF-NDMQHNLRLRSAVIMKMREYLINYLGFVEVETPTLFRRTP 632

  Fly   292 GGATAKPFVT------HHNDLKMDLFMRIAPELYHKMLVVGGLDRVYEIGRQFRNEGIDLTHNPE 350
            ||  |:.||.      |...|..      :|:.:.:||:.||:||.:::.|.:|:|.......||
  Fly   633 GG--AQEFVVPTRKAGHFYSLVQ------SPQQFKQMLMSGGIDRYFQVARCYRDEATRPDRQPE 689

  Fly   351 FTTCEFYMAYADYADIMDITEQ----------------------------------------LVS 375
            ||..:..:::....|||.:.|:                                        |::
  Fly   690 FTQLDIELSFTSRDDIMQLIEETLRYSWPKDFPRLQTPFRRITYEEAMEKYGNDKPDTRFGFLLN 754

  Fly   376 GMVKAIR------------GSYKVIYHPEGP----------EGPEQELDFTPPFKRVSMIKTLEE 418
            .:.:.|.            |:|.::......          |...:|...|...::....|.::|
  Fly   755 NVSEIIEKSDEFKEKYDDLGAYAIVVRASEAFWNGAARKHYESLGKEFKGTLFVRKFGPTKDVQE 819

  Fly   419 KL------QVKFPAADTFNSPETNQFLSQLCAKHQVECPAPRTTARLLDKLVGEFIEEFCVNPTF 477
            ||      .|....||.|:..|.:.....:.:|  ||      |..||.::..::.:       |
  Fly   820 KLGKLLGEDVATEVADKFDLEENDLLFLGIGSK--VE------TRELLGRIRLDYQD-------F 869

  Fly   478 ICEHPQIMSP-------------------------------------LAKYHRSIPGL----TER 501
            :.|:.:|..|                                     |..:..|...|    ::.
  Fly   870 LVENAKIKKPNDFRFLWVIDFPLFERNRETNQLESVHHPFTLPHSDDLENFATSCENLESIRSQA 934

  Fly   502 FELFVAKKEICNAYTELNDPVVQRERFEQQASDKAAGDDEAQLVDENFCTSLEYGLPPTGGFGMG 566
            ::|.:..:|:......::|..:|....||..  |...|..:.|:     ::||.|.||.||..:|
  Fly   935 YDLVLNGQEVGGGSIRIHDRDMQHFILEQIL--KIPHDHLSHLL-----SALESGCPPHGGIALG 992

  Fly   567 IDRLAMFLTDSNNIKEVLLFP 587
            :|||...|..:.:|::|:.||
  Fly   993 LDRLIAILCRARSIRDVIAFP 1013

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
LysRS	NP_001188571.1	PLN02502	42..593	CDD:215278	143/671 (21%)
		LysRS_N	141..250	CDD:239817	29/118 (25%)
		LysRS_core	253..591	CDD:238398	91/452 (20%)
AspRS-m	NP_001260520.2	RPA_2b-aaRSs_OBF_like	148..303	CDD:415809
		EcAspRS_like_N	291..410	CDD:239812	5/12 (42%)
		aspS	462..1045	CDD:234775	126/602 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45473203
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840