Protein Alignment LysRS and dars1

DIOPT Version :9

• Sequence 1: NP_001188571.1
• Gene: LysRS / 31904
• FlyBaseID: FBgn0027084
• Length: 607
• Species: Drosophila melanogaster
• Sequence 2: NP_001071079.1
• Gene: dars1 / 324025
• ZFINID: ZDB-GENE-061110-135
• Length: 531
• Species: Danio rerio
• Alignment Length: 606
• Identity: 132/606 - (21%)
• Similarity: 234/606 - (38%)
• Gaps: 150/606 - (24%)

  Fly    37 EPSKQTKLELKRRLKAEQKAKEKAEKAAAAPAENTAGKKKSSAAEEEEISPNEYFKLRSA----- 96
            |...|:|..||::.|..:||.:||||.|            ..|:|::|...:::.|.|..
Zfish    13 EQQAQSKKALKKQQKEAEKAAKKAEKQA------------KLASEQQETEEDDFAKDRYGICPMV 65

  Fly    97 -AVQELKRSPATDPYPHKFHVSSSLEDFIAKYENSLKEGETLENVKLSVAGRVHAIRESGAKLIF 160
             :.|:|.|:                  .:...:.:|::.|.    ::.|..|:|..|..| |..|
Zfish    66 QSQQKLDRA------------------LVRVQDLTLEKAEQ----QIWVRARIHTSRAKG-KQCF 107

  Fly   161 YDLRGEGVKVQVMASA--KSYKSEADFEIDTSKLRRGDIIGVVGHPGKTKKGE----------LS 213
            ..||.:...||.:.:.  ::.|....|..:.:|....|:..||      ||.|          :.
Zfish   108 LVLRHQQFTVQALLAVGDRASKQMVKFAANITKESIIDVEAVV------KKVEQKIESCSQQDVE 166

  Fly   214 VMPSEIKLLSPCLHMLPHLHFGLKD-----------------KETRYRQRYLDLILNNNVREKFQ 261
            :....|.::|.....||   ..|:|                 ::||...|.:||....: :..|:
Zfish   167 LHVERIFVISQSEARLP---LQLEDAVRPEGEGDEEGRATVNQDTRLDNRVIDLRTTTS-QAIFR 227

  Fly   262 IRAKIISYVRQFLDRLGFLEIETPMMNMIAGGATAKPFVTHHNDLKMDLFMRIAPELYHKMLVVG 326
            :::.:....|..|...||:||:||.:...|....|..|...:  .|...::..:|:||.:|.:..
Zfish   228 LQSGVCQLFRDTLINKGFVEIQTPKIISAASEGGANVFTVSY--FKTSAYLAQSPQLYKQMCICA 290

  Fly   327 GLDRVYEIGRQFRNEGIDL-THNPEFTTCEFYMAYA-DYADIMD-ITEQLVSGMVKAIRGSYKVI 388
            ..|:|:.:|..||.|..:. .|..||...:..||:: .|.:::| ||:.:|. :.|.:|..::..
Zfish   291 DFDKVFCVGPVFRAEDSNTHRHLTEFVGLDIEMAFSYHYHEVIDSITDTMVQ-IFKGLRDRFQTE 354

  Fly   389 YHPEGPEGPEQELDFTPPFKRVSMIKTLEEKLQVKFPAADTFNSPETNQFLSQLCAKHQVECPAP 453
            ......:.|.:...|..|..|:                       |..:.|:.|.|. .||....
Zfish   355 IQTVNKQYPSEPFKFLEPTLRL-----------------------EYKEGLAMLRAA-GVEMGDE 395

  Fly   454 RTTARLLDKLVGEFIEE-------------FCVNPTFICEHPQIMSPLAKYHRSIPGLTERFELF 505
            ...:...:||:|..::|             ..|.|.:....|.  :|  ||..|       :::|
Zfish   396 EDLSTPNEKLLGRLVKEKYDTDFYVLDKYPLAVRPFYTMPDPN--NP--KYSNS-------YDMF 449

  Fly   506 VAKKEICNAYTELNDPVVQRERFEQQASD----KAAGDDEAQLVDENFCTSLEYGLPPTGGFGMG 566
            :..:||.:....::|..:..||......|    ||            :..|..||.||..|.|:|
Zfish   450 MRGEEILSGAQRIHDAQLLTERAMHHNIDLEKIKA------------YIDSFRYGAPPHAGGGIG 502

  Fly   567 IDRLAMFLTDSNNIKEVLLFP 587
            ::|:.|.....:|:::..:||
Zfish   503 LERVTMLYLGLHNVRQTSMFP 523

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
LysRS	NP_001188571.1	PLN02502	42..593	CDD:215278	130/601 (22%)
		LysRS_N	141..250	CDD:239817	29/137 (21%)
		LysRS_core	253..591	CDD:238398	78/355 (22%)
dars1	NP_001071079.1	PLN02850	11..531	CDD:215456	132/606 (22%)
		AspRS_cyto_N	90..188	CDD:239815	25/107 (23%)
		AsxRS_core	204..527	CDD:238399	83/371 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910