Protein Alignment LysRS and kars-1

DIOPT Version :10

• Sequence 1: NP_727353.1
• Gene: LysRS / 31904
• FlyBaseID: FBgn0027084
• Length: 607
• Species: Drosophila melanogaster
• Sequence 2: NP_495454.1
• Gene: kars-1 / 174159
• WormBaseID: WBGene00002238
• Length: 596
• Species: Caenorhabditis elegans
• Alignment Length: 566
• Identity: 342/566 - (60%)
• Similarity: 429/566 - (75%)
• Gaps: 6/566 - (1%)

  Fly    41 QTKLELKRRLKAEQKAKEKAEKAAAAPAENTAGKKKSSAAEEEEISPNEYFKLRSAAVQELKRSP 105
            |...|.||..|..:|.:|:.||.||......|...| ...|.:...|.|||.:|...: |.:|:.
 Worm    32 QNTREQKRLAKQAKKEQERLEKDAAKLNVAVADAPK-VVREADPSDPQEYFNMRVRMI-EARRAA 94

  Fly   106 ATDPYPHKFHVSSSLEDFIAKYENSLKEGETLENVKLSVAGRVHAIRESGAKLIFYDLRGEGVKV 170
            ..:|:||||:|:.||.|||.|| ..|::.:.:|.: :|||||:|:.||||:||:|||:.|||..:
 Worm    95 GDNPFPHKFNVTISLTDFITKY-TPLEKEQVVEEI-VSVAGRIHSKRESGSKLVFYDIHGEGTHI 157

  Fly   171 QVMASAKSYKSEADFEIDTSKLRRGDIIGVVGHPGKTKKGELSVMPSEIKLLSPCLHMLPHLHFG 235
            |:||:||.:..:.||.....:::||||:|..|...:||.||||::|:||..|:||||||||.|||
 Worm   158 QIMANAKFHTGDVDFVTLHDRIKRGDIVGFTGRATRTKAGELSLIPNEILQLTPCLHMLPHSHFG 222

  Fly   236 LKDKETRYRQRYLDLILNNNVREKFQIRAKIISYVRQFLDRLGFLEIETPMMNMIAGGATAKPFV 300
            |||||.|:|:||||||||..|::.|.||:|||:::|::||.|||||:|||:||.||||||||||:
 Worm   223 LKDKELRFRKRYLDLILNPRVKDNFVIRSKIITFLRRYLDNLGFLEVETPIMNQIAGGATAKPFI 287

  Fly   301 THHNDLKMDLFMRIAPELYHKMLVVGGLDRVYEIGRQFRNEGIDLTHNPEFTTCEFYMAYADYAD 365
            ||||||.|:||:|:|||||||||||||:|||||:||.||||||||||||||||||||||||||.|
 Worm   288 THHNDLDMNLFLRVAPELYHKMLVVGGIDRVYEVGRLFRNEGIDLTHNPEFTTCEFYMAYADYED 352

  Fly   366 IMDITEQLVSGMVKAIRGSYKVIYHPEGPE-GPEQELDFTPPFKRVSMIKTLEEKLQVKFPAADT 429
            ::.:||.|:|.||.:|:|:||:.|||.||. .|..|:|||||||||.|...|.|||....|...|
 Worm   353 VIQLTEDLLSSMVMSIKGTYKIEYHPNGPNTEPVYEVDFTPPFKRVHMYDGLAEKLGATLPDPST 417

  Fly   430 FNSPETNQFLSQLCAKHQVECPAPRTTARLLDKLVGEFIEEFCVNPTFICEHPQIMSPLAKYHRS 494
            .::.|..:...:||..:.|:|.|||||||||||||||::|...::|||:..||||||||||:|||
 Worm   418 LHTEEAREVFDKLCRDNNVDCSAPRTTARLLDKLVGEYLESTFISPTFLIGHPQIMSPLAKWHRS 482

  Fly   495 IPGLTERFELFVAKKEICNAYTELNDPVVQRERFEQQASDKAAGDDEAQLVDENFCTSLEYGLPP 559
            |||||||||||...:||.|||||||||:.||:||||||.||.|||||||::||.||.:|||||||
 Worm   483 IPGLTERFELFAVTREIANAYTELNDPITQRQRFEQQAKDKDAGDDEAQMIDETFCNALEYGLPP 547

  Fly   560 TGGFGMGIDRLAMFLTDSNNIKEVLLFPAMKPEDANRTAAE-TAPT 604
            |||:|||||||:|.|||:||||||||||||:|||......: .|||
 Worm   548 TGGWGMGIDRLSMILTDNNNIKEVLLFPAMRPEDGTEKKTDFDAPT 593

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
LysRS	NP_727353.1	PLN02502	42..593	CDD:215278	336/551 (61%)
kars-1	NP_495454.1	PLN02502	35..581	CDD:215278	336/549 (61%)