DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rrp40 and RRP40

DIOPT Version :9

Sequence 1:	NP_001285565.1	Gene:	Rrp40 / 319033	FlyBaseID:	FBgn0260648	Length:	232	Species:	Drosophila melanogaster
Sequence 2:	NP_014499.2	Gene:	RRP40 / 854023	SGDID:	S000005502	Length:	240	Species:	Saccharomyces cerevisiae

Alignment Length:	214	Identity:	75/214 - (35%)
Similarity:	112/214 - (52%)	Gaps:	14/214 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 STIVMPGERIAAIEELAKSKRVILGPGLRRLDDT--VVASKAGPLRHKEPG-----TFWVDNYQR 62
            ||.:.||:..    .:..:..|.||||:....:|  :.....|.|.....|     |.::|...:
Yeast     2 STFIFPGDSF----PVDPTTPVKLGPGIYCDPNTQEIRPVNTGVLHVSAKGKSGVQTAYIDYSSK 62

  Fly    63 RYIPARGDLILGIVRAKAGDLYRVDI-GATDTASISYLAFEAASKKNRPDLIPGDLIYARVLNAS 126
            ||||:..|.::|::.....|.|:|.: ..:.:.|:||:||..|||||||.|..|||:||||..|.
Yeast    63 RYIPSVNDFVIGVIIGTFSDSYKVSLQNFSSSVSLSYMAFPNASKKNRPTLQVGDLVYARVCTAE 127

  Fly   127 ADIEPELVCVNS-VGKSGKLGVLTDGFFFKCSLNLGRMLLREN-CPVLAALTRELPYEIAVGVNG 189
            .::|.|:.|.:| .|:....|:|.||.....:||..|.||..| .|:|..|.....:|:|:|:||
Yeast   128 KELEAEIECFDSTTGRDAGFGILEDGMIIDVNLNFARQLLFNNDFPLLKVLAAHTKFEVAIGLNG 192

  Fly   190 RIWLKAHSLKETVALANAI 208
            :||:|...|..|:|....|
Yeast   193 KIWVKCEELSNTLACYRTI 211

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rrp40	NP_001285565.1	Rrp4	5..213	CDD:224022	75/214 (35%)
Rrp40	NP_001285565.1	S1_Rrp40	63..148	CDD:240216	36/86 (42%)
RRP40	NP_014499.2	Rrp4	1..240	CDD:224022	75/214 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157344717
Domainoid	1	1.000	74	1.000	Domainoid score	I2166
eggNOG	1	0.900	-	-		E1_COG1097
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6867
Inparanoid	1	1.050	122	1.000	Inparanoid score	I1299
Isobase	1	0.950	-	0.878984	Normalized mean entropy	S1604
OMA	1	1.010	-	-		QHG54235
OrthoFinder	1	1.000	-	-		FOG0004390
OrthoInspector	1	1.000	-	-		oto98985
orthoMCL	1	0.900	-	-		OOG6_102463
Panther	1	1.100	-	-	LDO	PTHR21321
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2268
SonicParanoid	1	1.000	-	-		X3108
TreeFam	1	0.960	-	-
	16	15.740