Protein Alignment Rrp40 and EXOSC3

DIOPT Version :10

• Sequence 1: NP_722725.1
• Gene: Rrp40 / 319033
• FlyBaseID: FBgn0260648
• Length: 232
• Species: Drosophila melanogaster
• Sequence 2: NP_057126.2
• Gene: EXOSC3 / 51010
• HGNCID: 17944
• Length: 275
• Species: Homo sapiens
• Alignment Length: 248
• Identity: 100/248 - (40%)
• Similarity: 157/248 - (63%)
• Gaps: 26/248 - (10%)

  Fly     7 IVMPGERI------------AAIE-------ELAKSKRVILGPGLRRLDDTVVASKAGPLRHKEP 52
            :|:|||.:            .|:|       ......||:.||||||..|.::.:|.|.||||||
Human    27 VVLPGEELLLPEQEDAEGPGGAVERPLSLNARACSRVRVVCGPGLRRCGDRLLVTKCGRLRHKEP 91

  Fly    53 GT------FWVDNYQRRYIPARGDLILGIVRAKAGDLYRVDIGATDTASISYLAFEAASKKNRPD 111
            |:      :|||:.|:||:|.:||.::|||.||:||:::||:|.::.||:|||:||.|:|:|||:
Human    92 GSGSGGGVYWVDSQQKRYVPVKGDHVIGIVTAKSGDIFKVDVGGSEPASLSYLSFEGATKRNRPN 156

  Fly   112 LIPGDLIYARVLNASADIEPELVCVNSVGKSGKLGVL-TDGFFFKCSLNLGRMLLRENCPVLAAL 175
            :..|||||.:.:.|:.|:|||:||::|.|::..:||: .||..||.:|.|.|.||..:|.::..:
Human   157 VQVGDLIYGQFVVANKDMEPEMVCIDSCGRANGMGVIGQDGLLFKVTLGLIRKLLAPDCEIIQEV 221

  Fly   176 TRELPYEIAVGVNGRIWLKAHSLKETVALANAISALEQSGCAEIDKICGNLGD 228
            .:..|.||..|:|||||:||.::::|:.|||.:.|.|.....:..:|...|.:
Human   222 GKLYPLEIVFGMNGRIWVKAKTIQQTLILANILEACEHMTSDQRKQIFSRLAE 274

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rrp40	NP_722725.1	Rrp40_N	23..63	CDD:436400	22/45 (49%)
		S1_Rrp40	63..148	CDD:240216	42/84 (50%)
		KH-I_Rrp40	150..226	CDD:411954	28/75 (37%)
EXOSC3	NP_057126.2	S1_Rrp40	108..193	CDD:240216	42/84 (50%)
		KH-I_Rrp40	196..273	CDD:411954	28/76 (37%)