DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rrp40 and exos-3

DIOPT Version :9

Sequence 1:	NP_001285565.1	Gene:	Rrp40 / 319033	FlyBaseID:	FBgn0260648	Length:	232	Species:	Drosophila melanogaster
Sequence 2:	NP_492751.1	Gene:	exos-3 / 186604	WormBaseID:	WBGene00010325	Length:	226	Species:	Caenorhabditis elegans

Alignment Length:	207	Identity:	76/207 - (36%)
Similarity:	122/207 - (58%)	Gaps:	4/207 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 TIVMPGERIAAIEELAKSKRVILGPGLRRLDDTVVASKAGPLRHKEPGTFWVDNYQRRYIPARGD 70
            |:.:||:   .|.|.:.|...|:|.|:.....|.:|::.|.. |.:.|..|::.:.:||||..||
Worm     2 TVYLPGD---VINEPSSSDSSIIGYGISVRGQTRIATQPGAF-HNDDGKVWLNVHSKRYIPQEGD 62

  Fly    71 LILGIVRAKAGDLYRVDIGATDTASISYLAFEAASKKNRPDLIPGDLIYARVLNASADIEPELVC 135
            .::.||.:|.||.:|:|||..:.|.|::..||.|:|:|||:|..||:|||.|.:.:...|.||.|
Worm    63 RVIAIVTSKTGDFFRLDIGTAEYAMINFTNFEGATKRNRPNLKTGDIIYATVFDTTPRTEAELTC 127

  Fly   136 VNSVGKSGKLGVLTDGFFFKCSLNLGRMLLRENCPVLAALTRELPYEIAVGVNGRIWLKAHSLKE 200
            |:...::..:|.|..||.||.|||..|.|:..:|.:|..:.:...:||.||:|||||:.|.:..:
Worm   128 VDDEKRARGMGQLNGGFMFKVSLNHCRRLINPSCKILQTVGKFFKFEITVGMNGRIWISASTSDD 192

  Fly   201 TVALANAISALE 212
            .:.:.:.|:..|
Worm   193 IIKIHDIINKSE 204

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rrp40	NP_001285565.1	Rrp4	5..213	CDD:224022	76/207 (37%)
Rrp40	NP_001285565.1	S1_Rrp40	63..148	CDD:240216	37/84 (44%)
exos-3	NP_492751.1	Rrp4	5..>187	CDD:224022	72/185 (39%)
exos-3	NP_492751.1	S1_Rrp40	55..140	CDD:240216	37/84 (44%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160162239
Domainoid	1	1.000	103	1.000	Domainoid score	I4280
eggNOG	1	0.900	-	-		E1_COG1097
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6867
Inparanoid	1	1.050	149	1.000	Inparanoid score	I2981
Isobase	1	0.950	-	0.878984	Normalized mean entropy	S1604
OMA	1	1.010	-	-		QHG54235
OrthoDB	1	1.010	-	-		D1284731at2759
OrthoFinder	1	1.000	-	-		FOG0004390
OrthoInspector	1	1.000	-	-		oto19177
orthoMCL	1	0.900	-	-		OOG6_102463
Panther	1	1.100	-	-	LDO	PTHR21321
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2268
SonicParanoid	1	1.000	-	-		X3108
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	16	15.790