DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG43755 and Rrbp1

DIOPT Version :9

Sequence 1:NP_001259819.1 Gene:CG43755 / 319026 FlyBaseID:FBgn0264086 Length:682 Species:Drosophila melanogaster
Sequence 2:NP_077243.2 Gene:Rrbp1 / 81910 MGIID:1932395 Length:1464 Species:Mus musculus


Alignment Length:515 Identity:114/515 - (22%)
Similarity:189/515 - (36%) Gaps:133/515 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly   128 YDRALKKSLKAAS-----LAPKPPKKSNIKPKWQLQKKPPQPGAFVLNRKCLKAKLERMPNIKRQ 187
            |:.||....|..:     ...|..|:..::.|.:.:||..:|     |.|..:..|:  ||:...
Mouse    38 YEEALANQRKEMAKTHHQKGEKKKKEKTVEKKGKTKKKEEKP-----NGKIPEHDLD--PNVTII 95

  Fly   188 LKS-----------NNVFSWL-HCP---QPADP-----SNPFDD-------SAVYPAIS------ 219
            ||.           .:|.|.: |.|   .||.|     |:|.|.       :.|.||:|      
Mouse    96 LKEPVRVSAVAVAPTSVHSSVGHTPIATVPAMPQEKLASSPKDRKKKEKKVAKVEPAVSSIVNSI 160

  Fly   220 ----IEQAMDMAKPEKPPKHGLRRKHWYCPPKCGEAESKCTDYEWAKYKMDPRPDNEAFQREMAN 280
                .:.|:..|.|::.|...:       ||...:|.|..|.   ::.|......|:|.:.|.|.
Mouse   161 QVLASKSAILEATPKEVPMVAV-------PPVGSKASSPATS---SQGKKGQGAQNQAKKGEGAQ 215

  Fly   281 QKAFKQPEPRNYDELYKSLVTCFVQDPNGKNDLCEALEKCCRDPKDPPAQGCSEFVPDGAGGD-- 343
            .:..|....:|             |...|:....:|.:......:....:|.......|.||.  
Mouse   216 NQGKKGEGAQN-------------QAKKGEGAQNQAKKGEGAQNQGKKGEGAQNQAKKGEGGQNQ 267

  Fly   344 ---GESAVDKDKGRDKDVDIDIHVDIDKDVDIDKDKRKDKG-----KTGDGDNENEGIGDGDGEK 400
               ||.|.::.|               |........:|.:|     |.|:|.......|:|...:
Mouse   268 AKKGEGAQNQGK---------------KGEGAQNQGKKGEGAQNQAKKGEGAQNQAKKGEGAQNQ 317

  Fly   401 G--GQNDKGKHEKGDGEGNKGSEKDGGEKKPAK--------------QNEVK-----ENDKEKGM 444
            |  |:..:.:.:||:|..|:..:.:||:.:..|              ||:.|     :|..:||:
Mouse   318 GKKGEGAQNQSKKGEGAQNQAKKGEGGQNQAKKGEGAQNQAKKGEGAQNQAKKGEGVQNQAKKGV 382

  Fly   445 EKGKEKGKE----KGKEKKTKEPNFRSSEDRPPVPQSK--DTTHGTEESHHGDGDFG-GPDGDRE 502
            |..:.:||:    :.:.||.:....::.:...|..|.|  :.....::...|..:.| .|:|...
Mouse   383 EGAQNQGKKGEANQNQAKKGEGGQNQTKKGEGPQNQGKKGEAAQKQDKKIEGAQNQGKKPEGTSN 447

  Fly   503 KGKN----QPDGKSGIVDQNQGKDKDKGKGKEKGMNKKGKGKKKPKDKDEDKNTKDNRSE 558
            :||.    |..||.|...|||||   ||:|.: ...|||:|.:....|.|....:..:.|
Mouse   448 QGKKGEGAQNQGKKGEGAQNQGK---KGEGAQ-NQGKKGEGAQNQGKKGEGAQNQGKKGE 503

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG43755NP_001259819.1 III <382..>425 CDD:164795 11/44 (25%)
Rrbp1NP_077243.2 Rib_recp_KP_reg 33..171 CDD:282899 32/139 (23%)
Tropomyosin 833..1081 CDD:278679
SPEC 877..1071 CDD:295325
PRK02224 968..>1448 CDD:179385
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_28NEJ
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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