Protein Alignment CG31915 and COLGALT1

DIOPT Version :9

• Sequence 1: NP_723087.1
• Gene: CG31915 / 319025
• FlyBaseID: FBgn0051915
• Length: 612
• Species: Drosophila melanogaster
• Sequence 2: NP_078932.2
• Gene: COLGALT1 / 79709
• HGNCID: 26182
• Length: 622
• Species: Homo sapiens
• Alignment Length: 600
• Identity: 256/600 - (42%)
• Similarity: 357/600 - (59%)
• Gaps: 41/600 - (6%)

  Fly    10 LLACILVCIS--------GQD----EEDYQ-----ESPTVLIALLVRNKAHILPMFLSYLEQQDY 57
            |||.:|:.::        |.|    ||.:.     ::|.||||||.||.||.||..|..||:..:
Human    15 LLALLLLLLAPLPPGAPPGADAYFPEERWSPESPLQAPRVLIALLARNAAHALPTTLGALERLRH 79

  Fly    58 PKERIAIWLRCDHSNDDSIELLRQWLDNSGDLYHSVSYEFKPEEQSFVNGTSPYEWPASRFKHLI 122
            |:||.|:|:..||:.|::..:||:||.....|||||.:....|.:|:.:...|..|..||::|::
Human    80 PRERTALWVATDHNMDNTSTVLREWLVAVKSLYHSVEWRPAEEPRSYPDEEGPKHWSDSRYEHVM 144

  Fly   123 ALKEEAFQYGRDIWADYVFFLDADVLLTSKDSLKVLTRLQLPIVAPMLISESLYSNFWCGMTEDY 187
            .|::.|.:..||:||||:.|:|||.|:.:.|:|.:|......:|||||.|.:.|||||||||...
Human   145 KLRQAALKSARDMWADYILFVDADNLILNPDTLSLLIAENKTVVAPMLDSRAAYSNFWCGMTSQG 209

  Fly   188 YYRRTDEYKEIYHVKKQGSFPVPMVHTAVLVNMNHRAVRNLTFDRNKLVELQKSRQQEPLYDGPA 252
            ||:||..|..|....::|.|.|||||:..|:::...|.|||.|           ....|.|....
Human   210 YYKRTPAYIPIRKRDRRGCFAVPMVHSTFLIDLRKAASRNLAF-----------YPPHPDYTWSF 263

  Fly   253 DDIIVFAISANSSGIPLHICNDITFGYILQPLEPGDTLDHDVQQLVNLK-SIMVNELGAVPPLLD 316
            |||||||.|...:.:.:::||...:|::..||....||..:.:..:::: .:||....|.|
Human   264 DDIIVFAFSCKQAEVQMYVCNKEEYGFLPVPLRAHSTLQDEAESFMHVQLEVMVKHPPAEP---- 324

  Fly   317 YYKHLEKKPEKS--KLSLDRIFMINLKRRPERREKMERLFDEIGIEAEHFPAVDGKELSTERLLE 379
              ......|.|:  |:..|.:|||||:||.:|||:|.|......||.....|||||.::|.::..
Human   325 --SRFISAPTKTPDKMGFDEVFMINLRRRQDRRERMLRALQAQEIECRLVEAVDGKAMNTSQVEA 387

  Fly   380 MGVRFLPGYEDPYHHRAMTMGEIGCFLSHYNIWVMMVRKQLKEVLILEDDIRFEPYFRQNAVRIL 444
            :|::.||||.||||.|.:|.||:||||||||||..:|.:.|::.|:.|||:|||.:|::..:.::
Human   388 LGIQMLPGYRDPYHGRPLTKGELGCFLSHYNIWKEVVDRGLQKSLVFEDDLRFEIFFKRRLMNLM 452

  Fly   445 NQA-RNAAQYDLIYFGRKRLK-EESEPAVENADNLVHAGYSYWTLGYVISLQGALKLLAAKPLDK 507
            ... |....:||||.||||:: |..|.||....|||.|.||||||.||||||||.|||||:||.|
Human   453 RDVEREGLDWDLIYVGRKRMQVEHPEKAVPRVRNLVEADYSYWTLAYVISLQGARKLLAAEPLSK 517

  Fly   508 LIPVDEFLPLMFDRHPNKTWTEAFPKRNLVAFSASPLLLYPIYYTGESGYISDTEDSQQISVETS 572
            ::|||||||:|||:||...:...|..|||.|||..|||:||.:|||:.||:||||.|...:.|..
Human   518 MLPVDEFLPVMFDKHPVSEYKAHFSLRNLHAFSVEPLLIYPTHYTGDDGYVSDTETSVVWNNEHV 582

  Fly   573 EEGEARLKSD--REQ 585
            :....|.||.  |||
Human   583 KTDWDRAKSQKMREQ 597

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31915	NP_723087.1	Glyco_tranf_GTA_type	32..>146	CDD:299700	49/113 (43%)
		Glyco_transf_25	334..515	CDD:133474	96/182 (53%)
COLGALT1	NP_078932.2	Glyco_tranf_GTA_type	56..>185	CDD:132997	53/128 (41%)
		Glyco_transf_25	340..525	CDD:294790	97/184 (53%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165159594
Domainoid	1	1.000	197	1.000	Domainoid score	I3095
eggNOG	1	0.900	-	-		E1_KOG4179
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	483	1.000	Inparanoid score	I1463
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG48029
OrthoDB	1	1.010	-	-		D327409at33208
OrthoFinder	1	1.000	-	-		FOG0001447
OrthoInspector	1	1.000	-	-		otm41364
orthoMCL	1	0.900	-	-		OOG6_101871
Panther	1	1.100	-	-	O	PTHR10730
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3744
SonicParanoid	1	1.000	-	-		X909
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	15	14.800