DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG31915 and Colgalt2

DIOPT Version :9

Sequence 1:	NP_723087.1	Gene:	CG31915 / 319025	FlyBaseID:	FBgn0051915	Length:	612	Species:	Drosophila melanogaster
Sequence 2:	XP_008767909.2	Gene:	Colgalt2 / 289081	RGDID:	1304702	Length:	625	Species:	Rattus norvegicus

Alignment Length:	584	Identity:	246/584 - (42%)
Similarity:	361/584 - (61%)	Gaps:	47/584 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 LACILVCIS---------------GQDEEDYQES----------PTVLIALLVRNKAHILPMFLS 50
            :||.|:.:|               .:.:||.:|:          |||.:.:|.||.||.||.||.
  Rat     8 VACALLLLSSALLRRGCPARFAAESESDEDGEETVAFPESPLQKPTVFVVVLARNAAHTLPHFLG 72

  Fly    51 YLEQQDYPKERIAIWLRCDHSNDDSIELLRQWLDNSGDLYHSVSYEFKPEEQSFVNGTSPYEWPA 115
            .||:.||||.|:|||...||:.|::.|:||:||.|...|||.|.:....|.:|:.:...|..||:
  Rat    73 CLERLDYPKSRMAIWAATDHNVDNTTEILREWLKNVQRLYHYVEWRPMDEPESYPDEIGPKHWPS 137

  Fly   116 SRFKHLIALKEEAFQYGRDIWADYVFFLDADVLLTSKDSLKVLTRLQLPIVAPMLISESLYSNFW 180
            |||.|::.|::.|.:..|:.|:||:.|:|.|..||:..:|.::......|:||||.|..||||||
  Rat   138 SRFAHVMKLRQAALRTAREKWSDYILFIDVDNFLTNPQTLNLMIAENKTILAPMLESRGLYSNFW 202

  Fly   181 CGMTEDYYYRRTDEYKEIYHVKKQGSFPVPMVHTAVLVNMNHRAVRNLTFDRNKLVELQKSRQQE 245
            ||:|...:|:||.:|.:|...|:.|.|||||||:..|:::...|...|:|         ....|:
  Rat   203 CGITPQGFYKRTPDYLQIREWKRTGCFPVPMVHSTFLIDLRKEASDKLSF---------YPPHQD 258

  Fly   246 PLYDGPADDIIVFAISANSSGIPLHICNDITFGYILQPLEPGDTLDHDVQQLVNLK-SIMVNELG 309
              |....|||||||.|:..:||.:::||...:||:..||:|..||..|::.|:::: ..|::.
  Rat   259 --YTWTFDDIIVFAFSSRQAGIQMYLCNKEHYGYLPIPLKPHQTLQEDIENLIHVQIEAMIDR-- 319

  Fly   310 AVPPL--LDYYKHLEKKPEKSKLSLDRIFMINLKRRPERREKMERLFDEIGIEAEHFPAVDGKEL 372
              ||:  ..:...:.|.|:  |:..|.|||||||||.:||::|.|...|..||.:...|||||.|
  Rat   320 --PPMEPSQFVSVVPKYPD--KMGFDEIFMINLKRRKDRRDRMLRTLYEQEIEVKIVEAVDGKAL 380

  Fly   373 STERLLEMGVRFLPGYEDPYHHRAMTMGEIGCFLSHYNIWVMMVRKQLKEVLILEDDIRFEPYFR 437
            :|.:|....:..||||.|||..|.:|.|||||||||:::|..::.::|::.|::|||:|||..|:
  Rat   381 NTSQLKAWNIEMLPGYRDPYSSRPLTRGEIGCFLSHFSVWKEVIDRELEKTLVIEDDVRFEHQFK 445

  Fly   438 QNAVRILNQARNA-AQYDLIYFGRKRLK-EESEPAVENADNLVHAGYSYWTLGYVISLQGALKLL 500
            :..:::::....| ..::|||.||||:: :|.|.||.|..|||.|.||||||||||||:||.||:
  Rat   446 RKLMKLMDDIDKARLDWELIYIGRKRMQVKEPEKAVPNVVNLVEADYSYWTLGYVISLEGAQKLV 510

  Fly   501 AAKPLDKLIPVDEFLPLMFDRHPNKTWTEAFPKRNLVAFSASPLLLYPIYYTGESGYISDTEDS 564
            .|.|..|::|||||||:|:::||...:.|.:..|:|.||||.|||:||.:|||:.||:||||.|
  Rat   511 GADPFGKMLPVDEFLPIMYNKHPVAEYKEYYESRDLKAFSAEPLLIYPTHYTGQPGYLSDTETS 574

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31915	NP_723087.1	Glyco_tranf_GTA_type	32..>146	CDD:299700	50/113 (44%)
CG31915	NP_723087.1	Glyco_transf_25	334..515	CDD:133474	92/182 (51%)
Colgalt2	XP_008767909.2	Glyco_tranf_2_4	61..174	CDD:404573	51/112 (46%)
Colgalt2	XP_008767909.2	Glyco_transf_25	340..525	CDD:382474	93/184 (51%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166353643
Domainoid	1	1.000	200	1.000	Domainoid score	I2940
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	473	1.000	Inparanoid score	I1442
OMA	1	1.010	-	-		QHG48029
OrthoDB	1	1.010	-	-		D327409at33208
OrthoFinder	1	1.000	-	-		FOG0001447
OrthoInspector	1	1.000	-	-		otm45487
orthoMCL	1	0.900	-	-		OOG6_101871
Panther	1	1.100	-	-	LDO	PTHR10730
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X909
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	13	12.910