Protein Alignment CG31915 and Colgalt2

DIOPT Version :10

• Sequence 1: NP_723087.1
• Gene: CG31915 / 319025
• FlyBaseID: FBgn0051915
• Length: 612
• Species: Drosophila melanogaster
• Sequence 2: NP_808424.3
• Gene: Colgalt2 / 269132
• MGIID: 2138232
• Length: 625
• Species: Mus musculus
• Alignment Length: 618
• Identity: 253/618 - (40%)
• Similarity: 365/618 - (59%)
• Gaps: 47/618 - (7%)

  Fly    11 LACILVCISG---------------QDEEDYQES----------PTVLIALLVRNKAHILPMFLS 50
            :||.|..:|.               ..:||.:|:          |||.:.:|.||.||.||.||.
Mouse     8 VACALFLLSSALLRLGCRARFAAEPDSDEDGEETVAFPESPPQKPTVFVVVLARNAAHTLPYFLG 72

  Fly    51 YLEQQDYPKERIAIWLRCDHSNDDSIELLRQWLDNSGDLYHSVSYEFKPEEQSFVNGTSPYEWPA 115
            .||:.||||.|:|||...||:.|::.|:||:||.:...|||.|.:....|.:|:.:...|..||.
Mouse    73 CLERLDYPKSRMAIWAATDHNVDNTTEILREWLKSVQRLYHYVEWRPMNEPESYPDEIGPKHWPN 137

  Fly   116 SRFKHLIALKEEAFQYGRDIWADYVFFLDADVLLTSKDSLKVLTRLQLPIVAPMLISESLYSNFW 180
            |||.|::.|::.|.:..|:.|:||:.|:|.|..||:..:|.::......||||||.|..||||||
Mouse   138 SRFSHVMKLRQAALRTAREKWSDYILFIDVDNFLTNPQTLNLMIVENKTIVAPMLESRGLYSNFW 202

  Fly   181 CGMTEDYYYRRTDEYKEIYHVKKQGSFPVPMVHTAVLVNMNHRAVRNLTFDRNKLVELQKSRQQE 245
            ||:|...:|:||.:|.:|...|:.|.|||||||:..|:::...|...|.|         ....|:
Mouse   203 CGITPQGFYKRTPDYLQIREWKRMGCFPVPMVHSTFLIDLRKEASDKLAF---------YPPHQD 258

  Fly   246 PLYDGPADDIIVFAISANSSGIPLHICNDITFGYILQPLEPGDTLDHDVQQLVNLK-SIMVNELG 309
              |....|||||||.|:..:||.:::||...:||:..||:|..||..||:.|:::: ..|::.
Mouse   259 --YTWTFDDIIVFAFSSRQAGIQMYLCNKEHYGYLPIPLKPHQTLQEDVENLIHVQIEAMIDH-- 319

  Fly   310 AVPPL--LDYYKHLEKKPEKSKLSLDRIFMINLKRRPERREKMERLFDEIGIEAEHFPAVDGKEL 372
              ||:  ..:...:.|.|:  |:..|.|||||||||.:||::|.|...|..||.:...|||||.|
Mouse   320 --PPMEPSQFVSVVPKYPD--KMGFDEIFMINLKRRKDRRDRMLRTLYEQEIEVKIVEAVDGKAL 380

  Fly   373 STERLLEMGVRFLPGYEDPYHHRAMTMGEIGCFLSHYNIWVMMVRKQLKEVLILEDDIRFEPYFR 437
            :|.:|....:..||||.|||..|.:|.|||||||||:::|..::.::|::.|::|||:|||..|:
Mouse   381 NTSQLKAWNIEMLPGYRDPYSSRPLTRGEIGCFLSHFSVWKEVIDRELEKTLVIEDDVRFEHQFK 445

  Fly   438 QNAVRILNQARNA-AQYDLIYFGRKRLK-EESEPAVENADNLVHAGYSYWTLGYVISLQGALKLL 500
            :..::::.....| ..::|||.||||:: :|.|.||.|..|||.|.||||||||.|||:||.||:
Mouse   446 RKLMKLMEDIDKAQLDWELIYIGRKRMQVKEPEKAVPNVVNLVEADYSYWTLGYAISLEGAQKLV 510

  Fly   501 AAKPLDKLIPVDEFLPLMFDRHPNKTWTEAFPKRNLVAFSASPLLLYPIYYTGESGYISDTEDSQ 565
            .|.|..|::|||||||:|:::||...:.|.:..|:|.||||.|||:||.:|||:.||:||||.|.
Mouse   511 GADPFGKMLPVDEFLPIMYNKHPVAEYKEYYESRDLKAFSAEPLLIYPTHYTGQPGYLSDTETST 575

  Fly   566 QISVETSEEGEARLKSDREQVFDHEQEFKLNPE 598
            ....||......|..|.:.:...|.:....|.|
Mouse   576 IWDNETVATDWDRTHSWKSRKQGHIRSTAKNTE 608

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31915	NP_723087.1	Glyco_tranf_GTA_type	32..>146	CDD:472172	49/113 (43%)
		COG3306	334..555	CDD:442535	112/222 (50%)
Colgalt2	NP_808424.3	Glyco_tranf_2_4	61..174	CDD:433416	50/112 (45%)
		Glyco_transf_25	340..525	CDD:470150	92/184 (50%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	597..625		3/12 (25%)
		Prevents secretion from ER. /evidence=ECO:0000255|PROSITE-ProRule:PRU10138	622..625