DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31915 and COX11

DIOPT Version :9

Sequence 1:	NP_723087.1	Gene:	CG31915 / 319025	FlyBaseID:	FBgn0051915	Length:	612	Species:	Drosophila melanogaster
Sequence 2:	NP_004366.1	Gene:	COX11 / 1353	HGNCID:	2261	Length:	276	Species:	Homo sapiens

Alignment Length:	135	Identity:	26/135 - (19%)
Similarity:	53/135 - (39%)	Gaps:	31/135 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 QDEEDYQESPTVL-------IALLVRNKAHILPMFLSYLEQQDYPKERIAIWLRCDHSNDDSIEL 78
            |:||..:::.|.|       :.:|..:.|.: |::..|.:........:|     .|:: |.||.
Human    84 QEEERRRQNKTTLTYVAAVAVGMLGASYAAV-PLYRLYCQTTGLGGSAVA-----GHAS-DKIEN 141

  Fly    79 LRQWLDN------SGDLYHSVSYEFKPEEQ-----------SFVNGTSPYEWPASRFKHLIALKE 126
            :....|.      :.|::.|:.:.|:|::.           :|....:|.:.|.........:..
Human   142 MVPVKDRIIKISFNADVHASLQWNFRPQQTEIYVVPGETALAFYRAKNPTDKPVIGISTYNIVPF 206

  Fly   127 EAFQY 131
            ||.||
Human   207 EAGQY 211

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31915	NP_723087.1	Glyco_tranf_GTA_type	32..>146	CDD:299700	22/124 (18%)
CG31915	NP_723087.1	Glyco_transf_25	334..515	CDD:133474
COX11	NP_004366.1	PTZ00128	62..265	CDD:185464	26/135 (19%)
COX11	NP_004366.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	64..92		3/7 (43%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3175
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900