DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Gga and tom1

DIOPT Version :9

Sequence 1:	NP_572571.1	Gene:	Gga / 31902	FlyBaseID:	FBgn0030141	Length:	660	Species:	Drosophila melanogaster
Sequence 2:	NP_001338580.1	Gene:	tom1 / 553244	ZFINID:	ZDB-GENE-060721-1	Length:	454	Species:	Danio rerio

Alignment Length:	482	Identity:	109/482 - (22%)
Similarity:	192/482 - (39%)	Gaps:	98/482 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 EMLERATNPAQKIDELGVQM-FCIVVKSNAQLVHKAQEMIVAKVR--------STNVTEATRAIS 65
            :::|.||:.:...::.|:.| .|       .||::|||.....||        :.|..|...|:|
Zfish    15 QLIEHATSSSLPSEDWGLNMEIC-------DLVNEAQEGPKDAVRAIKKRILGNRNFKEVMLALS 72

  Fly    66 LLEECMTQCGDDFQDEASKFRFL-NELIRLVSKKYKGAETPHEVKQRIMECLLLWTTEFPQRQKI 129
            :||.|:..||..|....|...|: |.|::.:..|   ...|..::.|::..:..|...|.....:
Zfish    73 VLEACVKNCGHKFHVYVSTRDFVENVLVQTILPK---NNAPVVLQDRVLIMIQAWADAFRSSTDL 134

  Fly   130 R---DAYDMLRKEGDIEHGTTE------AAVAKR--ESVLGTIDEAMFAKLIKSNNPENFKRANL 183
            .   ..|:.||:.| :|...||      ....||  |:| ..:.....:..:.|:.|:|.:....
Zfish   135 TGVVTVYEDLRRRG-VEFPMTELNGYSPIHTPKRSVENV-SPVKAHTESHPVTSSQPQNTETPVT 197

  Fly   184 LLQYRMAQEARRNDLLAQHRLVLCE---VQETMQLLNQMLDTYDPANQDVSET--LHELYKSCK- 242
            |...:|             :.:..|   |:..:.:::.|::..:||..:.|:|  |.:||...|
Zfish   198 LSPKQM-------------KTIKAELEVVRNNLSVMSDMMNQMEPATFEPSDTELLQQLYSMTKD 249

  Fly   243 KHKPIFQHLPQLLDDSDAQLVADTLDANCALLATMQRYKLLVPSPTRSTAAALTTSAPTVASSVK 307
            ....:.:.:|.|.|:   :|....|:||..:..|..:|.......:|.             ||.:
Zfish   250 MQSRMVEVIPTLTDE---KLTEQLLNANDDINTTFTQYHRFEKHLSRQ-------------SSAQ 298

  Fly   308 STASSTTATTSSNNAQLLNELLGDLLIDGSNKAATTATTSLPNAAASGSNPLADLSDIFSSALAE 372
            ..|.||..|...:..||          ..:|.|..:|.|:|.| ..||.:...|..:..||:|.:
Zfish   299 PNAPSTNLTDLDSPKQL----------KAANGAHQSAVTTLSN-QMSGLSTKEDDLNFKSSSLLK 352

  Fly   373 SEAKQQSQPFQNATTLLEP--QVISQGTTTEALANGNGG----SASKVPETIRK-MPQID----- 425
            |..:..:.......|.|:.  ...|.|::.:.|.....|    :.|:|.:.|.: :..:|
Zfish   353 SPERSAALATPGRDTGLDESRDSTSLGSSPQFLWMIEKGMIPVNQSEVMDDIEQWLDDVDDEDDS 417

  Fly   426 --MLSEELFQQILPTQ----DRMPSFK 446
              :.||| |.:.|..:    :|:||.|
Zfish   418 EGVTSEE-FDKFLAERAKAAERLPSVK 443

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Gga	NP_572571.1	VHS_GGA	7..144	CDD:239624	36/146 (25%)
		GAT	210..284	CDD:281166	18/76 (24%)
		Alpha_adaptinC2	543..644	CDD:197886
tom1	NP_001338580.1	VHS_ENTH_ANTH	12..152	CDD:321980	37/147 (25%)
tom1	NP_001338580.1	GAT_TOM1_like	203..289	CDD:260091	21/101 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170574133
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.840