Protein Alignment Gga and Tom1l2

DIOPT Version :10

• Sequence 1: NP_572571.1
• Gene: Gga / 31902
• FlyBaseID: FBgn0030141
• Length: 660
• Species: Drosophila melanogaster
• Sequence 2: NP_001390817.1
• Gene: Tom1l2 / 216810
• MGIID: 2443306
• Length: 528
• Species: Mus musculus
• Alignment Length: 543
• Identity: 109/543 - (20%)
• Similarity: 205/543 - (37%)
• Gaps: 115/543 - (21%)

  Fly    10 EMLERATNPAQKIDELGVQM-FCIVVKSNAQLVHKAQEMIVAKVR-STNVTEATRAISLLEECMT 72
            :.||:||:.:.:.::..:.| .|.::....:....|...:..::. :.|..|...|:::||.|:.
Mouse    15 QCLEKATDGSLQSEDWTLNMEICDIINETEEGPKDAIRALKKRLSGNRNYREVMLALTVLETCVK 79

  Fly    73 QCGDDFQDEASKFRFLNE-LIRLVSKKYKGAETPHEVKQRIMECLLLWTTEF---PQRQKIRDAY 133
            .||..|....:...|::. |::::|.|   ...|..|:.:::..:..|...|   |....:...|
Mouse    80 NCGHRFHLLVANRDFIDSVLVKIISPK---NNPPTIVQDKVLALIQAWADAFRSSPDLTGVVHIY 141

  Fly   134 DMLRKEG------DIE-----HGTTEAAVAKRESVLGTIDEAM-----FAKLIKSNNPENFKRAN 182
            :.|::.|      |::     | |.:.:|.:.:.. .||..:.     .|....|..|.::....
Mouse   142 EELKRRGIEFPMADLDALSPIH-TPQRSVPEMDPA-ATIPRSQTQPRTTAGTYSSPPPASYSTLQ 204

  Fly   183 LLLQYRMAQEARRNDLLAQHRLVLCEVQETMQLLNQMLDTYDPANQDVS--ETLHELYKSCKKHK 245
            .............::.:|:.|..|..|:...:::::||....|..:|.|  |.|.||.::|:
Mouse   205 APALSVTGPITANSEQIARLRSELDIVRGNTKVMSEMLTEMVPGQEDSSDLELLQELNRTCR--- 266

  Fly   246 PIFQH-LPQLLDD-SDAQLVADTLDANCALLATMQRYKL----------------LVPSPTRSTA 292
             ..|| :.:|:.. |:.::..:.|..|..|.....||:.                ::...|....
Mouse   267 -AMQHRIVELISRVSNEEVTEELLHVNDDLNNVFLRYERFERYRSGRSVQNASNGVLSEVTEDNL 330

  Fly   293 AALTTSAPTVASSVKSTASSTTATTSSNNAQLLNELLGDLLIDGSNKAATTATTSLPNAAASGSN 357
            ..|...:|.|.|.:    ..:||..||.::||....||...:.|:       .:||......
Mouse   331 IDLGPGSPAVVSPM----VGSTAPPSSLSSQLAGLDLGTESVSGT-------LSSLQQCKPQ--- 381

  Fly   358 PLADLSDIFSSALAESEAKQQSQPFQNATTLLEPQVISQGTTTEALAN--------GNGGSASKV 414
               |..|:|:.....|.|:|     :...|..:||.:  |....||.|        |.||.:...
Mouse   382 ---DGFDMFAQTRGNSLAEQ-----RKTVTYEDPQAV--GGLASALDNRKQNSEMRGRGGDSDLQ 436

  Fly   415 P-------------------ETIRKMPQIDMLSEELFQQILPTQDRMPSFKRDPEKI--TLNDLA 458
            |                   :.|....:.|:..::|.:.:  |.:....|..:..|.  |:.||
Mouse   437 PIDSWLMTQGMIPVAQPSVMDDIEVWLRTDLKGDDLEEGV--TSEEFDKFLEERAKAAETVPDL- 498

  Fly   459 RERMHIKAPEEPTTANDPASDSA 481
                    |..||.|..|||:::
Mouse   499 --------PSPPTEAPAPASNTS 513

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gga	NP_572571.1	VHS_GGA_metazoan	8..144	CDD:340769	29/150 (19%)
		GAT_GGA_meta	201..283	CDD:410582	22/101 (22%)
		Alpha_adaptinC2	543..644	CDD:197886
Tom1l2	NP_001390817.1	VHS_Tom1L2	12..148	CDD:340793	27/135 (20%)
		GAT_TM1L2	218..309	CDD:410585	23/94 (24%)