Protein Alignment Gga and TOM1

DIOPT Version :9

• Sequence 1: NP_572571.1
• Gene: Gga / 31902
• FlyBaseID: FBgn0030141
• Length: 660
• Species: Drosophila melanogaster
• Sequence 2: NP_001129204.1
• Gene: TOM1 / 10043
• HGNCID: 11982
• Length: 493
• Species: Homo sapiens
• Alignment Length: 548
• Identity: 105/548 - (19%)
• Similarity: 196/548 - (35%)
• Gaps: 133/548 - (24%)

  Fly    10 EMLERATNPAQKIDELGVQM-FCIVVKSNAQLVHKAQEMIVAK-VRSTNVTEATRAISLLEECMT 72
            :.:|:||:.:.:.::..:.| .|.::....:....|...:..: |.:.|..|...|:::||.|:.
Human    15 QRIEKATDGSLQSEDWALNMEICDIINETEEGPKDALRAVKKRIVGNKNFHEVMLALTVLETCVK 79

  Fly    73 QCGDDFQDEASKFRFLNE-LIRLVSKKYKGAETPHEVKQRIMECLLLWTTEF---PQRQKIRDAY 133
            .||..|....:...|:.. |:|.:..|   ...|..|..:::..:..|...|   |....:...|
Human    80 NCGHRFHVLVASQDFVESVLVRTILPK---NNPPTIVHDKVLNLIQSWADAFRSSPDLTGVVTIY 141

  Fly   134 DMLRKEGDIEHGTTEAAVAKRESVLGTIDEAMFAKLIKSNNPENFKRANLLLQYRMAQEARRNDL 198
            :.||::| :|...|:..:.   |.:.|....:|....:|.            |..:..::.:.:.
Human   142 EDLRRKG-LEFPMTDLDML---SPIHTPQRTVFNSETQSG------------QDSVGTDSSQQED 190

  Fly   199 LAQH--------------------------RLVLCEVQETMQLLNQMLDTYDPANQDVS--ETLH 235
            ..||                          |..|..|...::::::||....|...:.:  |.|.
Human   191 SGQHAAPLPAPPILSGDTPIAPTPEQIGKLRSELEMVSGNVRVMSEMLTELVPTQAEPADLELLQ 255

  Fly   236 ELYKSCK-KHKPIFQHLPQLLDDSDAQLVADTLDANCALLATMQRYKLLVPSPTRSTAAALTTSA 299
            ||.::|: ..:.:.:.:||:.::   ||..:.|..|..|.....|::......|     ..||.|
Human   256 ELNRTCRAMQQRVLELIPQIANE---QLTEELLIVNDNLNNVFLRHERFERFRT-----GQTTKA 312

  Fly   300 PTVASSVKS--TASSTTATTSSNNAQLLNELLGDLLIDGSNKAATTATTSLPNAAASGSNPLADL 362
            |:.|.....  ......|.|.:.::||.          |.|..:::....|.:..|||.  |.|.
Human   313 PSEAEPAADLIDMGPDPAATGNLSSQLA----------GMNLGSSSVRAGLQSLEASGR--LEDE 365

  Fly   363 SDIFS----SALAES-------------------EAKQQSQPFQNATTLLEPQVISQGTTTEALA 404
            .|:|:    |:||:.                   :|:|||......|.....:.|.|..:|:.
Human   366 FDMFALTRGSSLADQRKEVKYEAPQATDGLAGALDARQQSTGAIPVTQACLMEDIEQWLSTDV-- 428

  Fly   405 NGNGGSASKVPETIRKMPQIDMLSEELFQQILPTQDRMPSFKRDPEKITLNDLARERMHIKAPEE 469
                |:.::.|:.:....:.|...||..:    ..||:|:.                      ..
Human   429 ----GNDAEEPKGVTSEGKFDKFLEERAK----AADRLPNL----------------------SS 463

  Fly   470 PTTANDPASDSAPAIATATATVDSIDDV 497
            |:....|...|.||....|...|  ||:
Human   464 PSAEGPPGPPSGPAPRKKTQEKD--DDM 489

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gga	NP_572571.1	VHS_GGA	7..144	CDD:239624	29/139 (21%)
		GAT	210..284	CDD:281166	16/76 (21%)
		Alpha_adaptinC2	543..644	CDD:197886
TOM1	NP_001129204.1	VHS_Tom1	12..152	CDD:239623	30/140 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	171..212		4/52 (8%)
		GAT_TOM1	214..308	CDD:260094	20/101 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	307..336		7/28 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165141225
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D594067at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.850