Protein Alignment Mst27D and MAPRE3

DIOPT Version :10

• Sequence 1: NP_723253.2
• Gene: Mst27D / 319019
• FlyBaseID: FBgn0051907
• Length: 424
• Species: Drosophila melanogaster
• Sequence 2: NP_036458.2
• Gene: MAPRE3 / 22924
• HGNCID: 6892
• Length: 281
• Species: Homo sapiens
• Alignment Length: 338
• Identity: 71/338 - (21%)
• Similarity: 121/338 - (35%)
• Gaps: 109/338 - (32%)

  Fly    12 WTNMVKRVTASKYDVVSVKTLLMFINSKLDCELRGFEDLKTGAVYCQLMHRLFPNSIQIHKVKFY 76
            ::..|.....|::|      :|.::|..|.......|.|.:||.|||.|..|||..:.:.||||.
Human     6 YSTSVTSENLSRHD------MLAWVNDSLHLNYTKIEQLCSGAAYCQFMDMLFPGCVHLRKVKFQ 64

  Fly    77 TNDISDFQLNFRLLNNCFQKLRVTVYMPVHELTLG--HNQVVFCNWIYKFYEANDKGNEYDARKV 139
            .....::..||::|...|:|:.|...:||.:|..|  .:...|..|..||::||..|.:|:....
Human    65 AKLEHEYIHNFKVLQAAFKKMGVDKIIPVEKLVKGKFQDNFEFIQWFKKFFDANYDGKDYNPLLA 129

  Fly   140 RKGSPIGLDNSYKVASISTGSTCSVHKCQSMVFNYAKKPVRFERQNSLDALSFRPGIFKSIRREK 204
            |:|..:       ....:.|         ..:||.:||.:
Human   130 RQGQDV-------APPPNPG---------DQIFNKSKKLI------------------------- 153

  Fly   205 PTEQANPEPQQT-----KNIKKSSQFLAESKHVSLPSDSEDELELKAQKRYLQDQFVKKLNSSKN 264
                ....||:|     ||::.|.:.    .:|:.|.
Human   154 ----GTAVPQRTSPTGPKNMQTSGRL----SNVAPPC---------------------------- 182

  Fly   265 DEKTGTDATSKISEIPRPNPENEQLNTVCEKYEQETSDLRSNLNLIDKLELQLQNLQIDKEKLTN 329
                          |.|.||.:.:..    .:|.:...|..|..|:| |:|.:..|:.:::...:
Human   183 --------------ILRKNPPSARNG----GHETDAQILELNQQLVD-LKLTVDGLEKERDFYFS 228

  Fly   330 KLSRVESILNKHD 342
            ||..:|.|..:|:
Human   229 KLRDIELICQEHE 241

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mst27D	NP_723253.2	CH	27..128	CDD:425596	32/102 (31%)
MAPRE3	NP_036458.2	BIM1	16..279	CDD:227542	70/328 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	157..181		7/27 (26%)
		DCTN1-binding	217..281		6/25 (24%)
		APC-binding	217..260		6/25 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	261..281