DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31904 and Slc6a1

DIOPT Version :9

Sequence 1:	NP_723310.1	Gene:	CG31904 / 319016	FlyBaseID:	FBgn0260479	Length:	403	Species:	Drosophila melanogaster
Sequence 2:	NP_077347.1	Gene:	Slc6a1 / 79212	RGDID:	620533	Length:	599	Species:	Rattus norvegicus

Alignment Length:	205	Identity:	54/205 - (26%)
Similarity:	91/205 - (44%)	Gaps:	29/205 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    84 RGRWAKSADFYFASCTHAFSSLIFSELSTFGILHG--GWLLFIIAYLMGMLFYSLPIFLIQAFLG 146
            |..|....||..:...:|..   ...:..|..|.|  |...|:|.|.:.::|..:|:||::..||
  Rat    44 RDTWKGRFDFLMSCVGYAIG---LGNVWRFPYLCGKNGGGAFLIPYFLTLIFAGVPLFLLECSLG 105

  Fly   147 QFSSSGTISAFRVAPIFKGIGYAILLLNLGTLTYYSIAAVVPLIYTVNSIHPVIPWMSCNNSWNT 211
            |::|.|.:..:::||:|||:|.|..:|:.....||.:.....:.|..||....:||..|:|.|||
  Rat   106 QYTSIGGLGVWKLAPMFKGVGLAAAVLSFWLNIYYIVIISWAIYYLYNSFTTTLPWKQCDNPWNT 170

  Fly   212 QECSLHENYDVDFAVAVIFTLALAMGVQSSVIPLLSQVAGHGLSYTAVSGPAVVASPWAVPAAHW 276
            ..|  ..||          :|.....:.|:|:....:.. |.:: ..:..|..:         .|
  Rat   171 DRC--FSNY----------SLVNTTNMTSAVVEFWERNM-HQMT-DGLDKPGQI---------RW 212

  Fly   277 PAAVNVA-SW 285
            |.|:.:| :|
  Rat   213 PLAITLAIAW 222

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31904	NP_723310.1	SLC5-6-like_sbd	123..>243	CDD:294310	37/119 (31%)
CG31904	NP_723310.1	Cuticle_4	276..344	CDD:292577	5/11 (45%)
Slc6a1	NP_077347.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..23
		SLC6sbd_GAT1	2..599	CDD:212075	54/205 (26%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	577..599
		PDZ-binding	597..599
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11616
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000