DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31904 and slc6a4a

DIOPT Version :9

Sequence 1:	NP_723310.1	Gene:	CG31904 / 319016	FlyBaseID:	FBgn0260479	Length:	403	Species:	Drosophila melanogaster
Sequence 2:	NP_001035061.1	Gene:	slc6a4a / 664719	ZFINID:	ZDB-GENE-060314-1	Length:	646	Species:	Danio rerio

Alignment Length:	252	Identity:	71/252 - (28%)
Similarity:	113/252 - (44%)	Gaps:	47/252 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 ENSEHGTELPGDFIGEPVETESGGGMGGSLALAARRIRSRQVHSMAVRTGSAYDTLERP--YRH- 80
            |:.|:| .|..|.:.|. :.:||.|.|    ..:...||....|.....|:..|.:..|  :|.
Zfish    22 ESQENG-RLVVDSVPEK-DQKSGSGPG----QVSNGYRSTSPQSPKEGAGTGTDRVNTPGTFRTL 80

  Fly    81 -------DKCRGRWAKSADFYFASCTHA--------FSSLIFSELSTFGILHGGWLLFIIAYLMG 130
                   |..|..|:|..||..:...:|        |..:.:.        :||. .|::.||:.
Zfish    81 VVQQTSLDPPRETWSKKMDFLLSVIGYAVDLGNVWRFPYICYQ--------NGGG-AFLLPYLLM 136

  Fly   131 MLFYSLPIFLIQAFLGQFSSSGTISAFR-VAPIFKGIGYAILLLNLGTLTYYSIAAVVPLIYTVN 194
            .:|..:|:|.::..||||..||.||.:: |.|||||||:||.::.|....||:......|.|.::
Zfish   137 AVFGGVPLFYMELALGQFHRSGCISIWKHVCPIFKGIGFAICIIALYIAFYYNTIMAWALYYLLS 201

  Fly   195 SIHPVIPWMSCNNSWNTQECSLHENYDV-------------DFAVAVIFTLALAMGV 238
            |....:||.:|||.|||..|:.:.:.|:             :|.|..:..:.|:.|:
Zfish   202 SFRATLPWTTCNNRWNTPNCTHYLSTDLNVSWTNNSISPAEEFYVRQVLQVHLSPGL 258

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31904	NP_723310.1	SLC5-6-like_sbd	123..>243	CDD:294310	44/130 (34%)
CG31904	NP_723310.1	Cuticle_4	276..344	CDD:292577
slc6a4a	NP_001035061.1	SLC5-6-like_sbd	91..628	CDD:294310	53/177 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810