DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31904 and Slc6a8

DIOPT Version :9

Sequence 1:	NP_723310.1	Gene:	CG31904 / 319016	FlyBaseID:	FBgn0260479	Length:	403	Species:	Drosophila melanogaster
Sequence 2:	NP_059044.1	Gene:	Slc6a8 / 50690	RGDID:	619711	Length:	635	Species:	Rattus norvegicus

Alignment Length:	207	Identity:	55/207 - (26%)
Similarity:	88/207 - (42%)	Gaps:	50/207 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 SEHGTELPGDFI-----GEPVETESGGGMGGSLALAARRIRSRQVHSMAVRTGSAYDTLERPYRH 80
            |..|.|..|..|     |.|.:.:...|:|   |.::|         :||..
  Rat    12 SVSGDEKKGPLIVSGPDGAPSKGDGPAGLG---APSSR---------LAVPP------------- 51

  Fly    81 DKCRGRWAKSADFYFASCTHA--------FSSLIFSELSTFGILHGGWLLFIIAYLMGMLFYSLP 137
               |..|.:..||..:....|        |..|.:.        :||. :|:|.|::..|...:|
  Rat    52 ---RETWTRQMDFIMSCVGFAVGLGNVWRFPYLCYK--------NGGG-VFLIPYVLIALVGGIP 104

  Fly   138 IFLIQAFLGQFSSSGTISAFRVAPIFKGIGYAILLLNLGTLTYYSIAAVVPLIYTVNSIHPVIPW 202
            ||.::..||||..:|:|:.:.:.|:|||:|||.:::.....|||.:.......|.|.|....:||
  Rat   105 IFFLEISLGQFMKAGSINVWNICPLFKGLGYASMVIVFYCNTYYIMVLAWGFYYLVKSFTTTLPW 169

  Fly   203 MSCNNSWNTQEC 214
            .:|.::|||.:|
  Rat   170 ATCGHTWNTPDC 181

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31904	NP_723310.1	SLC5-6-like_sbd	123..>243	CDD:294310	33/92 (36%)
CG31904	NP_723310.1	Cuticle_4	276..344	CDD:292577
Slc6a8	NP_059044.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..47		11/46 (24%)
Slc6a8	NP_059044.1	SLC6sbd_CT1	52..621	CDD:271397	42/139 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11616
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100