DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31904 and Slc6a12

DIOPT Version :9

Sequence 1:	NP_723310.1	Gene:	CG31904 / 319016	FlyBaseID:	FBgn0260479	Length:	403	Species:	Drosophila melanogaster
Sequence 2:	NP_059031.1	Gene:	Slc6a12 / 50676	RGDID:	620255	Length:	628	Species:	Rattus norvegicus

Alignment Length:	190	Identity:	52/190 - (27%)
Similarity:	87/190 - (45%)	Gaps:	30/190 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    47 SLALAARRIRSRQ----VHSMAVRTGSAYDTLERPYRHDKCRGRWAKSADFYFASCTHAFSSLIF 107
            ||:...|::...:    |.|.....|...|..::....|  ||:|....:|..:         :.
  Rat    11 SLSSMDRKVTVHEDGCPVVSWVPEEGEMMDQKDKDQVKD--RGQWTNKMEFVLS---------VA 64

  Fly   108 SELSTFGIL---------HGGWLLFIIAYLMGMLFYS--LPIFLIQAFLGQFSSSGTISAFR-VA 160
            .|:...|.:         :||...||..::   .|:|  :|:|.::..|||:||.|:::|:| :.
  Rat    65 GEIIGLGNVWRFPYLCYKNGGGAFFIPYFI---FFFSCGIPVFFLEVALGQYSSQGSVTAWRKIC 126

  Fly   161 PIFKGIGYAILLLNLGTLTYYSIAAVVPLIYTVNSIHPVIPWMSCNNSWNTQECSLHENY 220
            |:.:|||.|.:::......||.|.....|.|..:|....:||.:|.|||||:.|....||
  Rat   127 PLLQGIGMASVVIESYLNIYYIIILAWALFYLFSSFTWELPWTTCTNSWNTEHCVDFLNY 186

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31904	NP_723310.1	SLC5-6-like_sbd	123..>243	CDD:294310	36/101 (36%)
CG31904	NP_723310.1	Cuticle_4	276..344	CDD:292577
Slc6a12	NP_059031.1	SLC5-6-like_sbd	49..589	CDD:294310	45/152 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11616
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000