DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31875 and MIDEAS

DIOPT Version :9

Sequence 1:	NP_001188765.1	Gene:	CG31875 / 318996	FlyBaseID:	FBgn0051875	Length:	161	Species:	Drosophila melanogaster
Sequence 2:	NP_001354639.1	Gene:	MIDEAS / 91748	HGNCID:	19853	Length:	1099	Species:	Homo sapiens

Alignment Length:	180	Identity:	35/180 - (19%)
Similarity:	63/180 - (35%)	Gaps:	62/180 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 PWKREQDLQQLQ-HRASILWSP--QLQDQDDK--AVREYLDYAAS-------------LYDIEEE 72
            |..|::.|.... |:|.::|.|  .|:...:|  .|.:.|..|.|             |:.:.|.
Human   734 PLMRDRALAAADPHKADLVWQPWEDLESSREKQRQVEDLLTAACSSIFPGAGTNQELALHCLHES 798

  Fly    73 QALFI-----------LRRHGYDLPLAHRRLEKTETARGCRYH-----RWKAEDLIRLTKAFEQY 121
            :...:           ||.|.:  |||             .||     :||..:.....|....|
Human   799 RGDILETLNKLLLKKPLRPHNH--PLA-------------TYHYTGSDQWKMAERKLFNKGIAIY 848

  Fly   122 GTDFAKVRKELPHFPLAE-LRLYFSFMSSA------------LETDDQQA 158
            ..||..|:|.:....:|: :..|:::....            ::|.|:::
Human   849 KKDFFLVQKLIQTKTVAQCVEFYYTYKKQVKIGRNGTLTFGDVDTSDEKS 898

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31875	NP_001188765.1	ELM2	18..63	CDD:279754	11/41 (27%)
MIDEAS	NP_001354639.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..69
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	99..159
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	228..264
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	276..305
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	330..349
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	378..397
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	410..441
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	543..563
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	887..1045		2/12 (17%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1194
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810