DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31875 and Mier2

DIOPT Version :9

Sequence 1:	NP_001188765.1	Gene:	CG31875 / 318996	FlyBaseID:	FBgn0051875	Length:	161	Species:	Drosophila melanogaster
Sequence 2:	XP_006514144.1	Gene:	Mier2 / 70427	MGIID:	1917677	Length:	563	Species:	Mus musculus

Alignment Length:	194	Identity:	45/194 - (23%)
Similarity:	72/194 - (37%)	Gaps:	63/194 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 RKQAATLPDFVPPWKREQDLQQL----------QHRASILWSPQLQDQDDKAVREYLDYAASLYD 68
            :|:....|.|      :.||..|          ::...:||||.:  ..::.|.|:| |.|....
Mouse   206 KKEIMVGPQF------QADLNILHLNRHCDKIYENEDQLLWSPSV--LPEREVEEFL-YRAVKRR 261

  Fly    69 IEE---------------EQALFILRRHGYDLPLAHRRLE-KTETARG--CRYHRWKAEDLIRLT 115
            .:|               ||||:.|.:..:::..|.|||. ..:..|.  |   .|..|:.....
Mouse   262 WQEMAGPQIPEGEVVKDSEQALYELVKCNFNVEEALRRLRFNVKVIRDGLC---AWSEEECRNFE 323

  Fly   116 KAFEQYGTDF-----AKVRKE-----LPHFPL---AELRLYFS---------FMSSALETDDQQ 157
            ..|..:|.:|     .|||..     :.::.|   :|...||:         |:||. .||.:|
Mouse   324 HGFRVHGKNFHLIQANKVRTRSVGECVEYYYLWKKSERYDYFAQQTRLGRRKFVSSG-TTDTEQ 386

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31875	NP_001188765.1	ELM2	18..63	CDD:279754	12/54 (22%)
Mier2	XP_006514144.1	ELM2	209..259	CDD:366648	14/58 (24%)
Mier2	XP_006514144.1	SANT_MTA3_like	314..358	CDD:212559	9/43 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1194
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810