DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31875 and MIER2

DIOPT Version :9

Sequence 1:	NP_001188765.1	Gene:	CG31875 / 318996	FlyBaseID:	FBgn0051875	Length:	161	Species:	Drosophila melanogaster
Sequence 2:	NP_001374081.1	Gene:	MIER2 / 54531	HGNCID:	29210	Length:	547	Species:	Homo sapiens

Alignment Length:	139	Identity:	29/139 - (20%)
Similarity:	52/139 - (37%)	Gaps:	38/139 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 RKQAATLPDFVPPWKREQDLQQL----------QHRASILWSPQLQDQDDKAVREYLDYAAS--L 66
            :|:....|.|      :.||..|          ::...:||.|.:  ..::.|.|:|..|..  .
Human   196 KKEIMVGPQF------QADLSNLHLNRHCEKIYENEDQLLWDPSV--LPEREVEEFLYRAVKRRW 252

  Fly    67 YDI------------EEEQALFILRRHGYDLPLAHRRLE-KTETARG--CRYHRWKAEDLIRLTK 116
            :::            :.||||:.|.:..:::..|.|||. ..:..|.  |   .|..|:......
Human   253 HEMAGPQLPEGEAVKDSEQALYELVKCNFNVEEALRRLRFNVKVIRDGLC---AWSEEECRNFEH 314

  Fly   117 AFEQYGTDF 125
            .|..:|.:|
Human   315 GFRVHGKNF 323

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31875	NP_001188765.1	ELM2	18..63	CDD:279754	11/54 (20%)
MIER2	NP_001374081.1	ELM2	199..249	CDD:396160	12/57 (21%)
MIER2	NP_001374081.1	SANT_MTA3_like	304..348	CDD:212559	5/20 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1194
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810