Protein Alignment Fum4 and Fum1

DIOPT Version :9

• Sequence 1: NP_723527.1
• Gene: Fum4 / 318995
• FlyBaseID: FBgn0051874
• Length: 484
• Species: Drosophila melanogaster
• Sequence 2: NP_572339.1
• Gene: Fum1 / 31605
• FlyBaseID: FBgn0286222
• Length: 495
• Species: Drosophila melanogaster
• Alignment Length: 469
• Identity: 289/469 - (61%)
• Similarity: 372/469 - (79%)
• Gaps: 2/469 - (0%)

  Fly    17 RLIVPDTRVEYDSMGAVHIPLDRMFGPQTMRSLMKFPIGGVEERMPRPLIKALGIVKKSAAETNK 81
            ||...:.|||.|:.|.:.:|.|:.:|.|||||.:.|||||..||||:|:::|:||:||:|||.||
  Fly    28 RLASQEFRVESDTFGELKVPADKYYGAQTMRSQINFPIGGATERMPKPVVQAMGILKKAAAEVNK 92

  Fly    82 IHCLEEHLCDAISKACDDVISGKLYDEEHFPLVIWQDGSGEHTNMNVNEVICNRAIEILGGQMGS 146
            ...|:..:.:|||||.|||||||||| :||||||||.|||..:||||||||.|||||:|||::||
  Fly    93 EFGLDSKVSEAISKAADDVISGKLYD-DHFPLVIWQTGSGTQSNMNVNEVISNRAIELLGGKLGS 156

  Fly   147 KEPVDPNEHVNMAQSSHDTFSTAVRIAVAMQLQETLYPSLRTFIDLLGKKSNDWMDLIKIGRTHL 211
            |.||.||:|||.:|||:|||.||:.|:||::|...|.|:::|..|.|..||.::.|:|||||||.
  Fly   157 KTPVHPNDHVNKSQSSNDTFPTAIHISVALELNNNLKPAIKTLHDALRAKSEEFKDIIKIGRTHT 221

  Fly   212 MDAVPLSLGQEFSGYQQQLVNGRTRLDCAMCRLYQLPMGGTSVGTKVDTKAEYSAQCIKRIAELT 276
            ||||||:||||||||.|||...:.|:|..:.|:|:|.:|||:|||.::|:..::.:|..:|||||
  Fly   222 MDAVPLTLGQEFSGYAQQLAYAQERIDACLPRVYELALGGTAVGTGLNTRKGFAEKCAAKIAELT 286

  Fly   277 FLPFVESPNFFESISACDCLVELHGELNTIAASVMKIANDIRFLGSGPRCGFGELHLPENEPGSS 341
            .||||.:||.||:::|.|.:||:||.|||||.|:|||||||||||||||||.|||.|||||||||
  Fly   287 SLPFVTAPNKFEALAARDAMVEVHGVLNTIAVSLMKIANDIRFLGSGPRCGLGELSLPENEPGSS 351

  Fly   342 IMPGKVNPTQCEAMSMICAQVMGNHVAVSMGGSSGHFQLNTFMPMIASNVLRSITLLGDGMKSFC 406
            ||||||||||||:::|:.||||||.|||::|||:|||:||.|.|:|.|||||||.||.||.::|.
  Fly   352 IMPGKVNPTQCESLTMLSAQVMGNQVAVTIGGSNGHFELNVFKPLIVSNVLRSIRLLSDGSRTFT 416

  Fly   407 TNCLEGIEPNRSKIGSIVKESLMLVTALSPHIGYERSAAIAKAAHHNGTTLEQEAI-LDGIQRED 470
            .||:.||:.||..|..|:.|||||||||:|||||:::|.|||.||.|||||::||| |..:..:.
  Fly   417 ANCVNGIQANRENIAKIMNESLMLVTALNPHIGYDKAAKIAKTAHKNGTTLKEEAINLGYLTEQQ 481

  Fly   471 FREWVQPSKMLGPE 484
            |.:||:|.:||||:
  Fly   482 FNDWVRPEQMLGPK 495

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Fum4	NP_723527.1	fumC	22..483	CDD:234779	285/461 (62%)
		Fumarase_classII	24..480	CDD:176465	283/456 (62%)
Fum1	NP_572339.1	fumC	31..495	CDD:234779	286/464 (62%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45471478
Domainoid	1	1.000	390	1.000	Domainoid score	I15
eggNOG	1	0.900	-	-		E1_COG0114
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	559	1.000	Inparanoid score	I15
Isobase	1	0.950	-	0	Normalized mean entropy	S145
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1022919at2759
OrthoFinder	1	1.000	-	-		FOG0002459
OrthoInspector	1	1.000	-	-		otm51349
orthoMCL	1	0.900	-	-		OOG6_101016
Panther	1	1.100	-	-	P	PTHR11444
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1641
	12	11.750