Protein Alignment Ada1-1 and TADA1

DIOPT Version :10

• Sequence 1: NP_723707.1
• Gene: Ada1-1 / 318991
• FlyBaseID: FBgn0051865
• Length: 308
• Species: Drosophila melanogaster
• Sequence 2: NP_444281.1
• Gene: TADA1 / 117143
• HGNCID: 30631
• Length: 335
• Species: Homo sapiens
• Alignment Length: 333
• Identity: 97/333 - (29%)
• Similarity: 150/333 - (45%)
• Gaps: 75/333 - (22%)

  Fly     8 ATKEALVVALGDNWERYRANMKNWFRSRWTKEEFDAESRKILTPDKLHLHNQFLLALLNKIDAFA 72
            |.|:.|..|||||.::|.||:|.||:.:.:|||||.|:.::||.|.:|.||.||||:|.:....
Human    10 AAKKNLSEALGDNVKQYWANLKLWFKQKISKEEFDLEAHRLLTQDNVHSHNDFLLAILTRCQIL- 73

  Fly    73 PLENPPAVQTSSSSGN--------------RSKRRKRSCR-TFAERLNFE--LSDVLDFVAEDNM 120
                   |.|...:|:              :.|::..|.| .|..|...:  ||....|||:|
Human    74 -------VSTPDGAGSLPWPGGSAAKPGKPKGKKKLSSVRQKFDHRFQPQNPLSGAQQFVAKD-- 129

  Fly   121 QIIRPPTTIGIPSDQQQQQLQSQRYCAQELFLPDAGFIMGRFLIGAWEIGLVSVDDNVAEYVAMA 185
                       |.|....:|     |:..:.||..|.:.||.::.|:|.||.:|.:.....|..|
Human   130 -----------PQDDDDLKL-----CSHTMMLPTRGQLEGRMIVTAYEHGLDNVTEEAVSAVVYA 178

  Fly   186 VQVLLKDLLSAIIKKRKHYKTSGEGNFYYDVGAPLR-DPSLRNTVTR-----------------Q 232
            |:..|||:|::::.:||.|:.. :|:|.|..|:.:. .|.|:|:|..                 |
Human   179 VENHLKDILTSVVSRRKAYRLR-DGHFKYAFGSNVTPQPYLKNSVVAYNNLIESPPAFTAPCAGQ 242

  Fly   233 KVDDTPLELDKELNTANFMRRQNDDVTFLSACE-EVQPTERTVITLKDCQLALR-DRNLIGSHAV 295
            .....|...|.|...|           .|.||. :..|.....:.:.|...||: .|.:|.:|.|
Human   243 NPASHPPPDDAEQQAA-----------LLLACSGDTLPASLPPVNMYDLFEALQVHREVIPTHTV 296

  Fly   296 YSINMERL 303
            |::|:||:
Human   297 YALNIERI 304

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ada1-1	NP_723707.1	SAGA-Tad1	10..>82	CDD:463692	31/71 (44%)
		HFD_TADA1	152..236	CDD:467058	29/101 (29%)
TADA1	NP_444281.1	SAGA-Tad1	7..193	CDD:463692	66/208 (32%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	83..103		1/19 (5%)
		HFD_TADA1	145..227	CDD:467058	28/82 (34%)