DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment LPCAT and LPGAT1

DIOPT Version :9

Sequence 1:	NP_001036265.1	Gene:	LPCAT / 31899	FlyBaseID:	FBgn0052699	Length:	533	Species:	Drosophila melanogaster
Sequence 2:	NP_001362773.1	Gene:	LPGAT1 / 9926	HGNCID:	28985	Length:	403	Species:	Homo sapiens

Alignment Length:	139	Identity:	31/139 - (22%)
Similarity:	52/139 - (37%)	Gaps:	53/139 - (38%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 TIKPTGGDEVP---------PAGVVGNVADVGVAASLTKRDSEEDTWASKGYNYINPFV------ 54
            |..|..|...|         ||......:.|.:|.:|     ||..|.  |:..:...:
Human     2 TATPRRGTPAPALRSRPPSAPAEKDRTESSVRMAITL-----EEAPWL--GWLLVKALMRFAFMV 59

  Fly    55 --HRIEIDSHIEVAKIYVLTVLLLPIRVVGC-------------VLSLISAWMFACIGLY-GMTL 103
              :.:.|.|:|    .||  ::|.|:||:..             :|.::::|     |.| |.|:
Human    60 VNNLVAIPSYI----CYV--IILQPLRVLDSKRFWYIEGIMYKWLLGMVASW-----GWYAGYTV 113

  Fly   104 ----DDLKA 108
                :|:||
Human   114 MEWGEDIKA 122

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
LPCAT	NP_001036265.1	PlsC	87..>265	CDD:223282	8/27 (30%)
		LPLAT_LPCAT1-like	126..338	CDD:153253
		EF-hand_8	455..507	CDD:290545
LPGAT1	NP_001362773.1	LPLAT_LCLAT1-like	102..318	CDD:153252	8/26 (31%)
LPGAT1	NP_001362773.1	Acyltransf_C	307..376	CDD:374349
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0204
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900