DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment LPCAT and GPAT3

DIOPT Version :9

Sequence 1:	NP_001036265.1	Gene:	LPCAT / 31899	FlyBaseID:	FBgn0052699	Length:	533	Species:	Drosophila melanogaster
Sequence 2:	XP_016864269.1	Gene:	GPAT3 / 84803	HGNCID:	28157	Length:	526	Species:	Homo sapiens

Alignment Length:	314	Identity:	76/314 - (24%)
Similarity:	138/314 - (43%)	Gaps:	47/314 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 VAASLTKRDSEED--TW-----ASKGYNYINPFVHRIEIDSHIEVAKIYVLTVL-----LLPIRV 80
            |...:|:|.|.|:  :|     .:..:.||:           :.:..::||.|:     |||:||
Human   200 VEDEVTQRFSSEELVSWNLLTRTNVNFQYIS-----------LRLTMVWVLGVIVRYCVLLPLRV 253

  Fly    81 VGCVLSLISAWMFACIGL----YGMTL-DDLKAKPLTGWRKQMQYMTACGMRMVYTFGSFHYVTM 140
            .           .|.||:    .|.|| ..|....|..|..::.::|.|.:.:....|:.||...
Human   254 T-----------LAFIGISLLVIGTTLVGQLPDSSLKNWLSELVHLTCCRICVRALSGTIHYHNK 307

  Fly   141 KGRAATAKEAPILVVAPHSSYVDSILVVASGPPSIVAKRETADIPLLGKIINYAQP-IYVQREDP 204
            :.|.....    :.||.|:|.:|.:::...|..::|.:.....:.::.:.:..|.| ::.:|.:.
Human   308 QYRPQKGG----ICVANHTSPIDVLILTTDGCYAMVGQVHGGLMGIIQRAMVKACPHVWFERSEM 368

  Fly   205 NSRQNTIRDIVDRARSTDDWPQVVIFAEGTCTNRTALIKFKPGAFYPGVPVQPVLLKYPNKYDTF 269
            ..|....:.:.:........| ::||.||||.|.|:::.||.|:|..|..:.||.:||..::...
Human   369 KDRHLVTKRLKEHIADKKKLP-ILIFPEGTCINNTSVMMFKKGSFEIGGTIHPVAIKYNPQFGDA 432

  Fly   270 TWTWDGPGVLRLLWLTMTQFYNRCEIEYLPVYTPSEDEVADANLYANNVREVMA 323
            .|......::..|...||.:...|::.|:|..|..|.|  ||..:||.|:..:|
Human   433 FWNSSKYNMVSYLLRMMTSWAIVCDVWYMPPMTREEGE--DAVQFANRVKSAIA 484

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
LPCAT	NP_001036265.1	PlsC	87..>265	CDD:223282	44/183 (24%)
		LPLAT_LPCAT1-like	126..338	CDD:153253	49/199 (25%)
		EF-hand_8	455..507	CDD:290545
GPAT3	XP_016864269.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0204
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810