DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment LPCAT and agpat5

DIOPT Version :9

Sequence 1:	NP_001036265.1	Gene:	LPCAT / 31899	FlyBaseID:	FBgn0052699	Length:	533	Species:	Drosophila melanogaster
Sequence 2:	NP_001070213.2	Gene:	agpat5 / 767778	ZFINID:	ZDB-GENE-060929-914	Length:	365	Species:	Danio rerio

Alignment Length:	342	Identity:	65/342 - (19%)
Similarity:	112/342 - (32%)	Gaps:	111/342 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    57 IEIDSHIEVAKIYVLTVLLLPIRVVGCVLSLISAWMFACIGLYGMTLDDLKAKPLTGWRKQMQYM 121
            :.:.:|...|...:..:|.:....:|.|..::.              |.||..||.||     |.
Zfish    88 VYLSNHQSTADWIIADMLAIRQNAIGHVRYVLK--------------DGLKWLPLYGW-----YF 133

  Fly   122 TACGMRMVYTFGSFHYVTMKGR--AATAKEAPI-LVVAPHSS-YVDSILVVASGPPSIVAKRETA 182
            :..|...|....:|....||.:  :.|....|: ||:.|..: |...:..|.|...:..||:..|
Zfish   134 SQHGGVYVKRSANFDEKAMKKKLSSQTRLSTPMYLVIFPEGTRYNPELKKVISDSQAFAAKQGLA 198

  Fly   183 DIPLLGKIINY-------AQPIYVQREDPNSRQNTIRDIVDRARSTDDWPQVVIFAEGTCTNRTA 240
                   ::|:       |..:.::         |:|:.:|...      .:.:..|||.|
Zfish   199 -------VLNHILTPRMKASHVAIE---------TMREHLDAVY------DITVAYEGTLT---- 237

  Fly   241 LIKFKPGAFYPGVPVQPVLL-----------------KYPNKYDTFTWTWDGPGVLRLLWLTMTQ 288
                ..|...| .|..|..|                 ..|.:.|.|..           ||
Zfish   238 ----ADGQRRP-APTMPEFLCKECPRVHIHISRVDIKDIPAEPDVFRG-----------WL---- 282

  Fly   289 FYNRCEI--EYLPVYTPSEDEVADANLYANNVREVMAKALGVPTSDYSFEDVIVMSRARDMKIPF 351
             :.|.||  :.|..:..|||....:.......:..::.:..:|:       ::::|     .:.|
Zfish   283 -HQRFEIKDKLLTTFYESEDPAKKSRFPGEGRKSPLSLSKTLPS-------LLILS-----GLTF 334

  Fly   352 PGDIVEIERTIEKLGLN 368
            |..:.|..|   ||.||
Zfish   335 PMLLTESGR---KLYLN 348

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
LPCAT	NP_001036265.1	PlsC	87..>265	CDD:223282	39/205 (19%)
		LPLAT_LPCAT1-like	126..338	CDD:153253	42/241 (17%)
		EF-hand_8	455..507	CDD:290545
agpat5	NP_001070213.2	LPLAT_LCLAT1-like	63..263	CDD:153252	43/224 (19%)
agpat5	NP_001070213.2	Acyltransf_C	258..327	CDD:292694	13/91 (14%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0204
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810