Protein Alignment LPCAT and AGPAT4

DIOPT Version :9

• Sequence 1: NP_001036265.1
• Gene: LPCAT / 31899
• FlyBaseID: FBgn0052699
• Length: 533
• Species: Drosophila melanogaster
• Sequence 2: NP_064518.1
• Gene: AGPAT4 / 56895
• HGNCID: 20885
• Length: 378
• Species: Homo sapiens
• Alignment Length: 195
• Identity: 43/195 - (22%)
• Similarity: 76/195 - (38%)
• Gaps: 57/195 - (29%)

  Fly    59 IDSHIEVAKIYVLTVLLLPI-----RVVGCVLS-LISAWMFACIGLYGMTLDDLKAKPLTGWRKQ 117
            |.|.:.:..|.:.|:||.||     |.:.|.|| .||:.:...:..:..|...:...|    |..
Human    22 IASGLIINTIQLFTLLLWPINKQLFRKINCRLSYCISSQLVMLLEWWSGTECTIFTDP----RAY 82

  Fly   118 MQYMTACGMRMVYTFGSFHYVTMKGRAATAKEAPILVVAPHSSYVDSI----------LVVASGP 172
            ::|                          .||..| ||..|...:|.:          |:   |.
Human    83 LKY--------------------------GKENAI-VVLNHKFEIDFLCGWSLSERFGLL---GG 117

  Fly   173 PSIVAKRETADIPLLGKIINYAQPIYVQREDPNSRQNTIRDIVDRARSTDDWPQ---VVIFAEGT 234
            ..::||:|.|.:|::|.:..:.:.::..|:....|: |:...:...|   |:|:   .:|..|||
Human   118 SKVLAKKELAYVPIIGWMWYFTEMVFCSRKWEQDRK-TVATSLQHLR---DYPEKYFFLIHCEGT 178

  Fly   235  234
            Human   179  178

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
LPCAT	NP_001036265.1	PlsC	87..>265	CDD:223282	31/161 (19%)
		LPLAT_LPCAT1-like	126..338	CDD:153253	25/122 (20%)
		EF-hand_8	455..507	CDD:290545
AGPAT4	NP_064518.1	PLN02380	20..345	CDD:178006	43/195 (22%)
		LPLAT_LCLAT1-like	62..256	CDD:153252	29/155 (19%)
		HXXXXD motif. /evidence=ECO:0000250|UniProtKB:Q9D517	96..101		1/4 (25%)
		Acyltransf_C	243..314	CDD:292694

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0204
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900