DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment LPCAT and AGPAT3

DIOPT Version :9

Sequence 1:	NP_001036265.1	Gene:	LPCAT / 31899	FlyBaseID:	FBgn0052699	Length:	533	Species:	Drosophila melanogaster
Sequence 2:	XP_011527964.1	Gene:	AGPAT3 / 56894	HGNCID:	326	Length:	463	Species:	Homo sapiens

Alignment Length:	207	Identity:	41/207 - (19%)
Similarity:	82/207 - (39%)	Gaps:	44/207 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    84 VLSLISAWMFACIGLYGMTLDDLKAKPLTGWRKQMQYMTACGMRMVYTFGSFHYVTMKGRAAT-- 146
            ||.|:..::|.   :.|:.::.::...|..|....|.......|:.|:..|...:.::..:.|
Human    99 VLHLLVGFVFV---VSGLVINFVQLCTLALWPVSKQLYRRLNCRLAYSLWSQLVMLLEWWSCTEC 160

  Fly   147 ------------AKEAPILVVAPHSSYVD-----------SILVVASGPPSIVAKRETADIPLLG 188
                        .||..:::: .|:..:|           .:|    |...::||:|...:||:|
Human   161 TLFTDQATVERFGKEHAVIIL-NHNFEIDFLCGWTMCERFGVL----GSSKVLAKKELLYVPLIG 220

  Fly   189 KIINYAQPIYVQREDPNSRQNTIRDIVDRARSTDDWPQ---VVIFAEGTCTNRTALIKFKPGAFY 250
            ....:.:.::.:|:....|..    :|:..|...|:|:   .:::.|||....|........|..
Human   221 WTWYFLEIVFCKRKWEEDRDT----VVEGLRRLSDYPEYMWFLLYCEGTRFTETKHRVSMEVAAA 281

  Fly   251 PGVPVQPVLLKY 262
            .|:||    |||
Human   282 KGLPV----LKY 289

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
LPCAT	NP_001036265.1	PlsC	87..>265	CDD:223282	39/204 (19%)
		LPLAT_LPCAT1-like	126..338	CDD:153253	33/165 (20%)
		EF-hand_8	455..507	CDD:290545
AGPAT3	XP_011527964.1	PLN02380	104..412	CDD:178006	38/202 (19%)
		LPLAT_LCLAT1-like	149..343	CDD:153252	30/154 (19%)
		Acyltransf_C	330..401	CDD:292694
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0204
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810