DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment LPCAT and Agpat1

DIOPT Version :9

Sequence 1:	NP_001036265.1	Gene:	LPCAT / 31899	FlyBaseID:	FBgn0052699	Length:	533	Species:	Drosophila melanogaster
Sequence 2:	NP_001156851.1	Gene:	Agpat1 / 55979	MGIID:	1932075	Length:	285	Species:	Mus musculus

Alignment Length:	266	Identity:	59/266 - (22%)
Similarity:	102/266 - (38%)	Gaps:	62/266 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    68 IYVLTVLLLPIRVVGCVLSLISAWMFACIGLYGMTLDDLKAKPLTGWRKQMQYMTACGMRMVYTF 132
            |..|.:|.:|:    |.:.             |..::::|...|.....:..|    |:| |...
Mouse    42 ILFLAILAIPV----CAVR-------------GRNVENMKILRLLLLHVKYLY----GIR-VEVR 84

  Fly   133 GSFHYVTMKGRAATAKEAPILVVAPHSSYVDSILVVASGPPSIV--AKRETADIPLLGKIINYAQ 195
            |:.|:...:         |.:||:.|.|.:|.:.::...|...|  ||||.......|.....|.
Mouse    85 GAHHFPPTQ---------PYVVVSNHQSSLDLLGMMEVLPDRCVPIAKRELLWAGSAGLACWLAG 140

  Fly   196 PIYVQREDPNSRQNTIRDIVDRARSTDDWPQVVIFAEGTCTNRTALIKFKPGAFY----PGVPVQ 256
            .|::.|:......:.:.::.....:.|  .:|.:|.|||..:..:::.||.|||:    ..||:.
Mouse   141 IIFIDRKRTGDAISVMSEVAQTLLTQD--VRVWVFPEGTRNHNGSMLPFKRGAFHLAVQAQVPII 203

  Fly   257 PVLLK-----YPNKYDTFTWTWDGPGVLRLLWLTMTQFYNRCEIEYLPVYTPSEDEVADANLYAN 316
            |:::.     |..|...||    .||              ||::..||..:.......|....|:
Mouse   204 PIVMSSYQDFYSKKERRFT----SPG--------------RCQVRVLPPVSTEGLTPDDVPALAD 250

  Fly   317 NVREVM 322
            :||..|
Mouse   251 SVRHSM 256

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
LPCAT	NP_001036265.1	PlsC	87..>265	CDD:223282	40/188 (21%)
		LPLAT_LPCAT1-like	126..338	CDD:153253	49/208 (24%)
		EF-hand_8	455..507	CDD:290545
Agpat1	NP_001156851.1	LPLAT_AGPAT-like	66..253	CDD:153251	49/220 (22%)
		HXXXXD motif. /evidence=ECO:0000250\|UniProtKB:Q9D517	101..106		2/4 (50%)
		EGTR motif. /evidence=ECO:0000250\|UniProtKB:Q99943	175..178		2/2 (100%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0204
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810