DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment LPCAT and gpat3

DIOPT Version :9

Sequence 1:	NP_001036265.1	Gene:	LPCAT / 31899	FlyBaseID:	FBgn0052699	Length:	533	Species:	Drosophila melanogaster
Sequence 2:	NP_001002685.1	Gene:	gpat3 / 436958	ZFINID:	ZDB-GENE-040718-436	Length:	449	Species:	Danio rerio

Alignment Length:	338	Identity:	79/338 - (23%)
Similarity:	148/338 - (43%)	Gaps:	51/338 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 VAASLTKRDSEED--TW-----ASKGYNYINPFVHRIEIDSHIEVAKIYVLTVLLLPIRVVGCVL 85
            |...:|:|.|.|:  :|     .:..:.||:.   |:.|   |....::|...:|||:|:...|:
Zfish   117 VEDQVTQRFSSEELASWNLLTRTNNNFRYISV---RLTI---IWGLGVFVRYCVLLPLRITLAVI 175

  Fly    86 SLISAWMFACIGLYGMTLDDLKAKPLTGWRKQMQYMTACGMRMVYTFGSFHYVTMKGRAATAK-- 148
            .|  :|:.....|.|. |.:.|.|   .|...:.::|.            :.:..:|.:||.:
Zfish   176 GL--SWLVIGTTLVGF-LPNSKVK---NWLSDLVHITC------------YRICARGLSATIRYH 222

  Fly   149 ------EAPILVVAPHSSYVDSILVVASGPPSIVAKRETADIPLLGKI----INYAQPIYVQRED 203
                  :...:.||.|:|.:|.:::...|..::|.:....   |:|.|    :.....::.:|.:
Zfish   223 NKENRPKKGGICVANHTSPIDIVILANDGCYAMVGQVHGG---LMGVIQRSMVRSCPHVWFERSE 284

  Fly   204 PNSRQNTIRDIVDRARSTDDWPQVVIFAEGTCTNRTALIKFKPGAFYPGVPVQPVLLKYPNKYDT 268
            ...|....:.:.|........| ::||.||||.|.|:::.||.|:|..|..:.||.:||..::..
Zfish   285 MKDRHAVAKRLKDHISDKTKLP-ILIFPEGTCINNTSVMMFKKGSFEFGGTIYPVAIKYDPRFGD 348

  Fly   269 FTWTWDGPGVLRLLWLTMTQFYNRCEIEYLPVYTPSEDEVADANLYANNVREVMAKALGVPTSDY 333
            ..|......::..:...||.:...|.:.|||..|..:.|  ||..:||.|:..:|...|:  .|.
Zfish   349 AFWNSAKYNMVSYILRMMTSWAIVCNVWYLPPMTQQDGE--DAVHFANRVKSAIAHQGGL--VDL 409

  Fly   334 SFEDVIVMSRARD 346
            |::..:..|:.::
Zfish   410 SWDGGLKRSKVKE 422

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
LPCAT	NP_001036265.1	PlsC	87..>265	CDD:223282	43/189 (23%)
		LPLAT_LPCAT1-like	126..338	CDD:153253	52/223 (23%)
		EF-hand_8	455..507	CDD:290545
gpat3	NP_001002685.1	LPLAT_LPCAT1-like	208..417	CDD:153253	52/216 (24%)
gpat3	NP_001002685.1	HXXXXD motif. /evidence=ECO:0000250\|UniProtKB:Q9D517	238..243		2/4 (50%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0204
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810