DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment LPCAT and tmem68

DIOPT Version :9

Sequence 1:	NP_001036265.1	Gene:	LPCAT / 31899	FlyBaseID:	FBgn0052699	Length:	533	Species:	Drosophila melanogaster
Sequence 2:	NP_956786.1	Gene:	tmem68 / 393464	ZFINID:	ZDB-GENE-040426-1267	Length:	331	Species:	Danio rerio

Alignment Length:	289	Identity:	54/289 - (18%)
Similarity:	90/289 - (31%)	Gaps:	95/289 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 DTWASKGY--NYINPFVHRIEIDSHIEVAKIY-VLTVLLLPIRVV-------------------- 81
            :.||..|.  :|:|...:.:.:.:.:.|..|. .|.|:||.:.::
Zfish    26 EEWAGLGQIEDYLNFLEYLVWVFTPLVVVFILPFLIVILLYLSILFLHVYKRKNQLREAYSNNLW 90

  Fly    82 -GCVLSLISAWMFACIGLYGMTLDDLKAKPLTGWRKQMQYMTACGMRMVYTFGSFHYVTMKGRAA 145
             |...:|.:.|.......:|..:..|...|..|....:.|..|..:...|...:  .:..|||..
Zfish    91 DGARKTLATLWDGHGAIWHGYEIHGLDKIPDEGPALIVYYHGAIPVDYYYFLAT--VIIQKGRTC 153

  Fly   146 TAKEAPILVVAPHSSYVDSILVVASGP-----------------PSIVAKRETAD--IPLL-GKI 190
            .:.....|...|....:..:..|..||                 |..|.:...:|  .||| ||.
Zfish   154 HSVADHFLFKVPGFKLLLEVFSVIHGPQEECVRALRNGHLLGISPGGVREALFSDETYPLLWGKR 218

  Fly   191 INYAQ----------PIYVQREDPNSRQ-----NTIRDIVDRARSTDDWPQVVIFAEGTCTNRTA 240
            ..:||          |::.|    |.|:     .|:|..                       |..
Zfish   219 KGFAQVAIDSKVPVIPMFTQ----NLREGFRSLGTLRFF-----------------------RWV 256

  Fly   241 LIKFKPGAFYPGVPVQPVLLKYPNKYDTF 269
            ..:|:       :||.|:...:|.|:.||
Zfish   257 YERFR-------LPVAPIYGGFPVKFRTF 278

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
LPCAT	NP_001036265.1	PlsC	87..>265	CDD:223282	39/212 (18%)
		LPLAT_LPCAT1-like	126..338	CDD:153253	34/179 (19%)
		EF-hand_8	455..507	CDD:290545
tmem68	NP_956786.1	PlsC	51..310	CDD:223282	49/264 (19%)
tmem68	NP_956786.1	LPLAT_MGAT-like	104..311	CDD:153249	40/211 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0204
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900