DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment LPCAT and aup1

DIOPT Version :9

Sequence 1:	NP_001036265.1	Gene:	LPCAT / 31899	FlyBaseID:	FBgn0052699	Length:	533	Species:	Drosophila melanogaster
Sequence 2:	XP_005173140.1	Gene:	aup1 / 324654	ZFINID:	ZDB-GENE-030131-3375	Length:	429	Species:	Danio rerio

Alignment Length:	328	Identity:	70/328 - (21%)
Similarity:	115/328 - (35%)	Gaps:	85/328 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   162 VDSILVVASGPPSIVAKRETADIPLLGKIINYAQPIYVQREDPNSRQNTIR-------------- 212
            |...||..:.|.|||.:       .:.:|:.....::||:..|..|..|.|
Zfish    44 VHVFLVSCALPDSIVRR-------FIVRIMCSVLGLHVQQNSPRLRDKTTRLYVCNHVTHFDHNI 101

  Fly   213 ---------------------------------------DIVDRARSTDDWPQVVIFAEGTCTN- 237
                                                   :.:.|..|:.|...:::|.|...||
Zfish   102 INLLTSCNTPLLEGPVGFLCWARGFMELGQGVGSRTELTETLHRYCSSPDTLPLLLFPEEDTTNG 166

  Fly   238 RTALIKFKPGAFYPGVPVQPVLLKYPNKYDTFTWTWDGPGVLRLLWLTMTQF--YNRCEIEYLPV 300
            ||.|:||....|.....:|||.|.....:...: |.:...:..|||.....|  |:   :.:||.
Zfish   167 RTGLLKFSSWPFSVSDSIQPVALLVKRPFIAVS-TPESSWLTELLWTFFVPFTVYH---VRWLPP 227

  Fly   301 YTPSEDEVADANLYANNVREVMAKALGVPTSDYSFEDV---IVMSR------ARDMKIPFPGDIV 356
            .:..:.|....  :|:.|:.::|..|||.::..:..|.   |...|      |...|..| .|:.
Zfish   228 LSKEDGETHQE--FASKVQGLLATELGVISTQITKADKAEHIKRKRHSAPQTAHSSKNGF-NDLG 289

  Fly   357 EIERTIEK--LGLN---ESQRDAELCKGFLRLSNTDRLDIITFGELLQVDLKNTDLHKLFALLDH 416
            ...||:.:  ||.:   |..|.|.|.:....:.....:.:|| .:|||.:..:|.:..|....|.
Zfish   290 ARPRTVAQGFLGTSVGAEDSRIARLAQQVKEVLPDVPVSVIT-RDLLQTNCVDTTITNLLERTDQ 353

  Fly   417 RRS 419
            ..|
Zfish   354 FNS 356

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
LPCAT	NP_001036265.1	PlsC	87..>265	CDD:223282	31/156 (20%)
		LPLAT_LPCAT1-like	126..338	CDD:153253	46/231 (20%)
		EF-hand_8	455..507	CDD:290545
aup1	XP_005173140.1	LPLAT	63..263	CDD:302626	39/205 (19%)
aup1	XP_005173140.1	CUE_AUP1	310..354	CDD:270603	11/44 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0204
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810