DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment LPCAT and Gpat3

DIOPT Version :9

Sequence 1:	NP_001036265.1	Gene:	LPCAT / 31899	FlyBaseID:	FBgn0052699	Length:	533	Species:	Drosophila melanogaster
Sequence 2:	NP_001020841.1	Gene:	Gpat3 / 305166	RGDID:	1565703	Length:	457	Species:	Rattus norvegicus

Alignment Length:	314	Identity:	78/314 - (24%)
Similarity:	141/314 - (44%)	Gaps:	47/314 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 VAASLTKRDSEED--TW-----ASKGYNYINPFVHRIEIDSHIEVAKIYVLTVL-----LLPIRV 80
            |...:|:|.|.|:  :|     .:..::||:|           ::..::||.||     |||:||
  Rat   108 VEDEVTQRFSSEELVSWNLLTRTNVNFHYISP-----------KLTIVWVLGVLVRYCFLLPLRV 161

  Fly    81 ----VGCVLSLISAWMFACIGLYGMTL-DDLKAKPLTGWRKQMQYMTACGMRMVYTFGSFHYVTM 140
                :|..|.:|           |.|| ..|....|..|..::.::|.|.:.:....|:.||...
  Rat   162 TLAFIGISLLII-----------GTTLVGQLPDSSLKNWLSELVHLTCCRICVRSLSGTIHYHNK 215

  Fly   141 KGRAATAKEAPILVVAPHSSYVDSILVVASGPPSIVAKRETADIPLLGKIINYAQP-IYVQREDP 204
            :.|.....    :.||.|:|.:|.:::...|..::|.:.....:.::.:.:..|.| ::.:|.:.
  Rat   216 QYRPQKGG----ICVANHTSPIDVLILATDGCYAMVGQVHGGLMGIIQRAMVKACPHVWFERSEI 276

  Fly   205 NSRQNTIRDIVDRARSTDDWPQVVIFAEGTCTNRTALIKFKPGAFYPGVPVQPVLLKYPNKYDTF 269
            ..|....:.:.:........| ::||.||||.|.|:::.||.|:|..|..:.||.:||..::...
  Rat   277 KDRHLVTKRLKEHIADKKKLP-ILIFPEGTCINNTSVMMFKKGSFEIGGTIYPVAIKYNPQFGDA 340

  Fly   270 TWTWDGPGVLRLLWLTMTQFYNRCEIEYLPVYTPSEDEVADANLYANNVREVMA 323
            .|......::..|...||.:...|::.|:|..|..|.|  ||..:||.|:..:|
  Rat   341 FWNSSKYNLVSYLLRIMTSWAIVCDVWYMPPMTREEGE--DAVQFANRVKSAIA 392

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
LPCAT	NP_001036265.1	PlsC	87..>265	CDD:223282	42/179 (23%)
		LPLAT_LPCAT1-like	126..338	CDD:153253	49/199 (25%)
		EF-hand_8	455..507	CDD:290545
Gpat3	NP_001020841.1	LPLAT_LPCAT1-like	199..408	CDD:153253	50/201 (25%)
		HXXXXD motif. /evidence=ECO:0000250\|UniProtKB:Q9D517	229..234		2/4 (50%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	429..457
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0204
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810