DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment LPCAT and Agpat3

DIOPT Version :9

Sequence 1:	NP_001036265.1	Gene:	LPCAT / 31899	FlyBaseID:	FBgn0052699	Length:	533	Species:	Drosophila melanogaster
Sequence 2:	NP_001099848.1	Gene:	Agpat3 / 294324	RGDID:	1305787	Length:	376	Species:	Rattus norvegicus

Alignment Length:	201	Identity:	36/201 - (17%)
Similarity:	78/201 - (38%)	Gaps:	64/201 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    62 HIEVAKIYVLTVLLLPIRVVGCVLSL--ISAWMFA---CIGLYGMTLDDLKAKPLTGWRKQMQYM 121
            |:.:..::|::.|::....: |.|:|  ||..::.   |...|.:            |.:.:..:
  Rat    14 HLLIGFVFVVSGLIINFTQL-CTLALWPISKNLYRRINCRLAYSL------------WSQLVMLL 65

  Fly   122 -----TACGM----RMVYTFGSFHYVTMKGRAATAKEAPILVVAPHSSYVD-----------SIL 166
                 |.|.:    ..|..||..|               ::|:..|:..:|           .:|
  Rat    66 EWWSCTECTLFTDQATVNHFGKEH---------------VVVILNHNFEIDFLCGWTMCERFGVL 115

  Fly   167 VVASGPPSIVAKRETADIPLLGKIINYAQPIYVQREDPNSRQNTIRDIVDRARSTDDWPQ---VV 228
                |...::||||...:||:|....:.:.::.:|:....|..    :::..|...::|:   .:
  Rat   116 ----GSSKVLAKRELLYVPLIGWTWYFLEIVFCKRKWEEDRDT----VIEGLRRLANYPEYMWFL 172

  Fly   229 IFAEGT 234
            ::.|||
  Rat   173 LYCEGT 178

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
LPCAT	NP_001036265.1	PlsC	87..>265	CDD:223282	31/176 (18%)
		LPLAT_LPCAT1-like	126..338	CDD:153253	23/127 (18%)
		EF-hand_8	455..507	CDD:290545
Agpat3	NP_001099848.1	PLN02380	12..325	CDD:178006	36/201 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0204
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900