DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment LPCAT and acl-1

DIOPT Version :9

Sequence 1:	NP_001036265.1	Gene:	LPCAT / 31899	FlyBaseID:	FBgn0052699	Length:	533	Species:	Drosophila melanogaster
Sequence 2:	NP_510606.1	Gene:	acl-1 / 181671	WormBaseID:	WBGene00010339	Length:	262	Species:	Caenorhabditis elegans

Alignment Length:	289	Identity:	59/289 - (20%)
Similarity:	105/289 - (36%)	Gaps:	66/289 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    65 VAKIYVLTVLLL--PIRVVGCVLSLISAWMFACIG--LYGMTLDDLKAKPLTGWR--KQMQYMT- 122
            :|.::|:.||||  .:.|:|..:..:...|...||  |.|:........|...:|  |..|.||
Worm     4 LAILFVIAVLLLLAQLPVIGFYIRAVYFGMCLIIGGFLGGLASIPFGKSPNNHFRMFKIFQAMTW 68

  Fly   123 ACGMRMVYTFGSFHYVTMKGRAATAKEAPILVVAPHSSYVDSILVVASGPPS--IVAKRETADIP 185
            ..|:|.          .::.......:.|.:::|.|.|.:|.:.:..:.|..  ::.|.....:|
Worm    69 PMGVRF----------ELRNSEILHDKKPYIIIANHQSALDVLGMSFAWPVDCVVMLKSSLKYLP 123

  Fly   186 LLGKIINYAQPIYVQREDPNSR----QNTIRDIVDRARSTDDWPQVVIFAEGTCTNRTALIKFKP 246
            ...........:|:.|......    ..|:.:||.:.|      :|.|:.|||......|:.||.
Worm   124 GFNLCAYLCDSVYINRFSKEKALKTVDTTLHEIVTKKR------KVWIYPEGTRNAEPELLPFKK 182

  Fly   247 GAF----YPGVPVQPVLLKYPNKYDTFTWTWDGPGVLRLLWLTMTQFYN---------RCEIEYL 298
            |||    ...:|:.|.:.. .:|:                      ||:         .|.|:.|
Worm   183 GAFILAKQAKIPIVPCVFS-SHKF----------------------FYSHAEKRLTSGNCIIDIL 224

  Fly   299 PVYTPSE-DEVADANLYANNVREVMAKAL 326
            |....|: |.:.|.:.:...:.:...:.|
Worm   225 PEVDSSKFDSIDDLSAHCRKIMQAHREKL 253

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
LPCAT	NP_001036265.1	PlsC	87..>265	CDD:223282	40/192 (21%)
		LPLAT_LPCAT1-like	126..338	CDD:153253	39/221 (18%)
		EF-hand_8	455..507	CDD:290545
acl-1	NP_510606.1	PlsC	26..>199	CDD:223282	40/188 (21%)
acl-1	NP_510606.1	LPLAT_AGPAT-like	65..243	CDD:153251	41/216 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0204
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810