DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment LPCAT and acl-12

DIOPT Version :9

Sequence 1:	NP_001036265.1	Gene:	LPCAT / 31899	FlyBaseID:	FBgn0052699	Length:	533	Species:	Drosophila melanogaster
Sequence 2:	NP_509260.1	Gene:	acl-12 / 181001	WormBaseID:	WBGene00015295	Length:	391	Species:	Caenorhabditis elegans

Alignment Length:	385	Identity:	72/385 - (18%)
Similarity:	125/385 - (32%)	Gaps:	144/385 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly    54 VHRIEID---SHIEVAKIYVLTVLLLPIRVVGCVL--SLISAWMFACIGLYGMTLDDLKAKPLTG 113
            ||.|||.   |.:..|..:.:|..::|   |.||:  ||:...|.....|:......|.|.....
Worm    30 VHLIEIRRIISLVGAAYFFFMTAWVVP---VACVITVSLLFPLMLFSTPLFNYLEHKLCAMVNAH 91

  Fly   114 WRKQMQYMTACGMRMVYTFGSFHYVTMKGRAATAKEAPILVVAPHSSYVDSILVVAS--GPPSIV 176
            |.....::.|    .|..:|:    .:.|.|    |...|::|.|...:|..:::.|  |..||.
Worm    92 WNAVSVFVGA----TVTEYGT----NLAGYA----EEKCLLLANHLGLLDHFVLMQSLNGKGSIR 144

  Fly   177 AKRETADIPLLGKIINYAQPIY-----------------------VQREDPNSRQNTIRDIVDRA 218
            ::              :...||                       |.:.|  |..::.||.:..:
Worm   145 SR--------------WMWVIYNIWKYTPLGVMWTSHGNFFVNGGVSKRD--SVLSSFRDHLKNS 193

  Fly   219 RSTDDWPQVVIFAEGTCTNRTALIK-----------FKP--GAFYP------------------- 251
            ....|:..|:::.||   :|..|:|           .||  ...||
Worm   194 FYKYDYGWVIMYPEG---SRLYLVKNSGRTFAEKNGLKPLDNCVYPRTGAAHAVLDVLGPTDDSL 255

  Fly   252 -------GVPVQPVL---LKY-----PNKYDTFTWTWDGPGVLRLLWLTMTQFYNRCEIEYLPVY 301
                   |.|::.::   :.|     |:..|.....|:.        :..:||....::
Worm   256 SMSKCGKGEPIKYIIDATIGYRKGAVPDICDVMMGDWES--------VEASQFAVHYDV------ 306

  Fly   302 TPSEDEVADANLYANNVREVMAKALGVPTSDYSFEDVIVMSR--ARDMKI-PFPGDIVEI 358
            .|.:.|.:|.||                ..::.:|..|:..:  |...|. .||||..::
Worm   307 IPVKPEWSDENL----------------LKEFLYERYIIKDKLLAEFYKTGHFPGDKTKV 350

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
LPCAT	NP_001036265.1	PlsC	87..>265	CDD:223282	42/249 (17%)
		LPLAT_LPCAT1-like	126..338	CDD:153253	45/283 (16%)
		EF-hand_8	455..507	CDD:290545
acl-12	NP_509260.1	LPLAT	<156..290	CDD:302626	21/138 (15%)
acl-12	NP_509260.1	Acyltransf_C	302..364	CDD:292694	13/71 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0204
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900