DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment LPCAT and F44B9.5

DIOPT Version :9

Sequence 1:	NP_001036265.1	Gene:	LPCAT / 31899	FlyBaseID:	FBgn0052699	Length:	533	Species:	Drosophila melanogaster
Sequence 2:	NP_498746.1	Gene:	F44B9.5 / 176127	WormBaseID:	WBGene00018408	Length:	390	Species:	Caenorhabditis elegans

Alignment Length:	419	Identity:	91/419 - (21%)
Similarity:	147/419 - (35%)	Gaps:	111/419 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 PPAGVVGNVADVGVAASLTKRDSEEDTWASKGYNYINPFVHRIEIDSHIEVAKIYVLTVLLLPIR 79
            |.|...||..|:.: ..|..:...|||                       :|||:  :::..|
Worm     4 PEASSSGNTEDLRI-EDLFHQKRNEDT-----------------------IAKIF--SIIYAP-- 40

  Fly    80 VVGCVLSLISAWMFACIGLYGMTLDDLKAKPLTGWRKQMQYMTACGMRMVYTFGSFHYVTMKGRA 144
             ||.::.||..:    :|.:...:..|..|........::.|  |.:..:....|.|
Worm    41 -VGLIILLIRVF----LGFHTFIVACLLRKSAALRMHTLRIM--CSILGIVVEKSGH-------- 90

  Fly   145 ATAKEAPILVVAPHSSYVDSILVVASGP---PSIVAKRETADIPLLGKIINYAQPIYVQREDPNS 206
              ..|:..::.|.|.|.:|.:.|....|   ||:      .|||   .||.:... ||.......
Worm    91 --RDESARVLCANHVSILDHLAVDILTPCLLPSV------WDIP---SIIRWCFG-YVDLGATRG 143

  Fly   207 RQNTIRDIVDRARS--TDDWPQVVIFAEGTCTN-RTALIKFKPGAFYPGVPVQPVLLK----YPN 264
            |.    .:|.||:.  |.:...::.|.||..|: ..|||||....|.....||||.::    ||.
Worm   144 RD----QLVSRAKQLLTREQMPLLAFPEGIITSGEKALIKFNTWCFEVSSVVQPVSVRVWRPYPW 204

  Fly   265 KYDTFTWTWDGPGVLRLLWLTMTQFY------NRCEIEYLPVYTPSEDEVADANLYANNVREVMA 323
            |...        .||...|.| ..||      ....:||||.....|:|..:.  :...|.|.:|
Worm   205 KVSV--------SVLGSSWWT-DLFYFFALPFTVITVEYLPKMERRENESLEE--FTARVAETLA 258

  Fly   324 KALGVPTSDYSFEDV----------------IVMSRARDMKIPFPGDIVE----IERTIEKLGLN 368
            ..|.:..|.:...|.                :|:......::..|..:.|    |:::.....|:
Worm   259 GNLKIAVSKFGISDATEAAKRLRTDRERAKKVVVREKTSPRLADPRQMDECAMRIKQSFPSFHLS 323

  Fly   369 ESQRDAELCKGFLRLSNTDRLDIITFGEL 397
            ..:||.|..:     |.|..::.:..|::
Worm   324 AIRRDLEKTR-----SQTTTVNNLKAGKI 347

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
LPCAT	NP_001036265.1	PlsC	87..>265	CDD:223282	46/187 (25%)
		LPLAT_LPCAT1-like	126..338	CDD:153253	57/227 (25%)
		EF-hand_8	455..507	CDD:290545
F44B9.5	NP_498746.1	LPLAT	75..279	CDD:302626	60/240 (25%)
F44B9.5	NP_498746.1	CUE	305..346	CDD:214715	8/45 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0204
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810