DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment LPCAT and Agpat4

DIOPT Version :9

Sequence 1:	NP_001036265.1	Gene:	LPCAT / 31899	FlyBaseID:	FBgn0052699	Length:	533	Species:	Drosophila melanogaster
Sequence 2:	XP_006227918.1	Gene:	Agpat4 / 170919	RGDID:	619916	Length:	414	Species:	Rattus norvegicus

Alignment Length:	303	Identity:	62/303 - (20%)
Similarity:	103/303 - (33%)	Gaps:	111/303 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly    59 IDSHIEVAKIYVLTVLLLPI----------RVVGCVLS----LISAWMFACIGLYGMTLDDLKAK 109
            |.|.:.|..|.:.|:::.||          |:..||.|    |:..|......:|    .|.||.
  Rat    58 IASGLIVNAIQLCTLVIWPINKQLFRKINARLCYCVSSQLVMLLEWWSGTECTIY----TDPKAS 118

  Fly   110 PLTGWRKQMQYMTACGMRMVYTFGSFHYVTMKGRAATAKEAPILVVAPHSSYVD----------- 163
            |                         ||         .||..| ||..|...:|
  Rat   119 P-------------------------HY---------GKENAI-VVLNHKFEIDFLCGWSLAERL 148

  Fly   164 SILVVASGPPSIVAKRETADIPLLGKIINYAQPIYVQREDPNSRQNTIRDIVDRARSTDDWPQVV 228
            .||    |...::||:|.|.:|::|.:..:.:.|:..|:....||...:.::    ...|:|:..
  Rat   149 GIL----GNSKVLAKKELAYVPIIGWMWYFVEMIFCTRKWEQDRQTVAKSLL----HLRDYPEKY 205

  Fly   229 IF---AEGT--------CTNRTALIKFKPGAFYPGVP--------------VQPVL----LKYPN 264
            :|   .|||        .:.:.|..|..|...:..:|              |.|.:    |.:.|
  Rat   206 LFLIHCEGTRFTEKKHQISMQVAQAKGLPSLKHHLLPRTKGFAITVKCLRDVVPAVYDCTLNFRN 270

  Fly   265 KYDTFTWTWDGPGVLRLLWLTMTQFYNRCEIEYLPVYTPSEDE 307
            .        :.|.:|.:  |...:::..|.:..:|:....|||
  Rat   271 N--------ENPTLLGV--LNGKKYHADCYVRRIPMEDIPEDE 303

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
LPCAT	NP_001036265.1	PlsC	87..>265	CDD:223282	42/217 (19%)
		LPLAT_LPCAT1-like	126..338	CDD:153253	44/222 (20%)
		EF-hand_8	455..507	CDD:290545
Agpat4	XP_006227918.1	PlsC	51..325	CDD:223282	62/303 (20%)
		LPLAT_LCLAT1-like	98..292	CDD:153252	47/250 (19%)
		Acyltransf_C	279..350	CDD:292694	6/27 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0204
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810