DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Naa20B and NAA10

DIOPT Version :9

Sequence 1:	NP_001285885.1	Gene:	Naa20B / 318982	FlyBaseID:	FBgn0051851	Length:	204	Species:	Drosophila melanogaster
Sequence 2:	NP_003482.1	Gene:	NAA10 / 8260	HGNCID:	18704	Length:	235	Species:	Homo sapiens

Alignment Length:	186	Identity:	55/186 - (29%)
Similarity:	87/186 - (46%)	Gaps:	24/186 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 EDLFKFNNIVMDPLAEVYSLPFLLPKILEHPELVLAADAPDNSLMGFILGTRVEDATESFGDAKT 74
            |||....:..:..|.|.|.:.:.....|..|:|...|:..:..::|::|....||..:.
Human     9 EDLMNMQHCNLLCLPENYQMKYYFYHGLSWPQLSYIAEDENGKIVGYVLAKMEEDPDDV------ 67

  Fly    75 MTWNHGHISALAVAQDYRKLGLGTRLLTTV-RDMMDRQKDFYIDLFVREKNTIAIGLY-ESLGYV 137
               .||||::|||.:.:|:|||..:|:... |.|::.....|:.|.||:.|..|:.|| .:|.:.
Human    68 ---PHGHITSLAVKRSHRRLGLAQKLMDQASRAMIENFNAKYVSLHVRKSNRAALHLYSNTLNFQ 129

  Fly   138 KYRWIPKFYAD-DHGYEMRLPLSSDVD--RKSLE----------GIIIKKIYSFGN 180
            .....||:||| :..|.|:..|:...|  |:.||          |.|..|:.|.||
Human   130 ISEVEPKYYADGEDAYAMKRDLTQMADELRRHLELKEKGRHVVLGAIENKVESKGN 185

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Naa20B	NP_001285885.1	RimI	<27..158	CDD:223532	39/133 (29%)
Naa20B	NP_001285885.1	Acetyltransf_1	50..137	CDD:278980	27/88 (31%)
NAA10	NP_003482.1	RimI	1..149	CDD:223532	44/148 (30%)
		Interaction with NAA15. /evidence=ECO:0000269\|PubMed:15496142	1..58		11/48 (23%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	178..235		4/8 (50%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0456
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.810