DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31832 and angptl2a

DIOPT Version :9

Sequence 1:	NP_723894.2	Gene:	CG31832 / 318970	FlyBaseID:	FBgn0051832	Length:	227	Species:	Drosophila melanogaster
Sequence 2:	NP_001025401.1	Gene:	angptl2a / 569092	ZFINID:	ZDB-GENE-080721-15	Length:	525	Species:	Danio rerio

Alignment Length:	173	Identity:	72/173 - (41%)
Similarity:	117/173 - (67%)	Gaps:	5/173 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    56 WIVIQRRLDGSVNFNQSWFSYKDGFGDPNGEFFIGLQKLYLMTREQPHELFIQLKHGPGATVYAH 120
            |.|||||:||||||.::|.:||.|||:.:||:::||:.:|.:|.:..::|.:.|:...|...:|.
Zfish   348 WTVIQRRMDGSVNFFRNWETYKQGFGNIDGEYWLGLENIYWLTNQGNYKLLVTLEDWSGRKTFAE 412

  Fly   121 FDDFQVDSETELYKLERVGKYSGTAGDSLRYHINKRFSTFDRDNDESSKNCAAEHGGGWWFHSCL 185
            :..|:::.|.:.||: |||:|.|.||||:.:|..|:|:|.|||:|..:.|||....||||:::|.
Zfish   413 YASFRLEPEADFYKM-RVGRYHGNAGDSMTWHNGKQFTTLDRDHDAYTGNCAHYQKGGWWYNACA 476

  Fly   186 SSSLNGLYFREG--ETGMLNGIHWGRWK--FQSLTFVQIMIRP 224
            .|:|||:::|.|  .:...:|::|..::  ..||..|.:||||
Zfish   477 HSNLNGVWYRGGHYRSRYQDGVYWAEFRGGSYSLKKVTMMIRP 519

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31832	NP_723894.2	FReD	28..225	CDD:238040	72/173 (42%)
angptl2a	NP_001025401.1	DUF1875	<50..>147	CDD:286100
		Fib_alpha	119..215	CDD:285864
		FReD	305..519	CDD:238040	70/171 (41%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2579
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X25
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810