DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31832 and ANGPT4

DIOPT Version :9

Sequence 1:	NP_723894.2	Gene:	CG31832 / 318970	FlyBaseID:	FBgn0051832	Length:	227	Species:	Drosophila melanogaster
Sequence 2:	NP_057069.1	Gene:	ANGPT4 / 51378	HGNCID:	487	Length:	503	Species:	Homo sapiens

Alignment Length:	203	Identity:	76/203 - (37%)
Similarity:	116/203 - (57%)	Gaps:	9/203 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 SPNGIHQLMLPEEEPFQVTQC--KTTARDWIVIQRRLDGSVNFNQSWFSYKDGFGDPNGEFFIGL 91
            |.:|::.:.:......:...|  :::...|.:||||.:|:|||.::|..||.|||||.||.::|.
Human   300 SASGVYTIQVSNATKPRKVFCDLQSSGGRWTLIQRRENGTVNFQRNWKDYKQGFGDPAGEHWLGN 364

  Fly    92 QKLYLMTREQPHELFIQLKHGPGATVYAHFDDFQVDSETELYKLERVGKYSGTAG--DSLRYHIN 154
            :.::.:||...:.|.::|:...|...||.::.|.:.||.:||:|..|| |||:||  .||... |
Human   365 EVVHQLTRRAAYSLRVELQDWEGHEAYAQYEHFHLGSENQLYRLSVVG-YSGSAGRQSSLVLQ-N 427

  Fly   155 KRFSTFDRDNDESSKNCAAEHGGGWWFHSCLSSSLNGLYFREGETG-MLNGIHWGRWK--FQSLT 216
            ..|||.|.|||.....||....|||||.:|..|:|||:|:...:.. .::||.|..:|  ..||.
Human   428 TSFSTLDSDNDHCLCKCAQVMSGGWWFDACGLSNLNGVYYHAPDNKYKMDGIRWHYFKGPSYSLR 492

  Fly   217 FVQIMIRP 224
            ..::||||
Human   493 ASRMMIRP 500

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31832	NP_723894.2	FReD	28..225	CDD:238040	76/203 (37%)
ANGPT4	NP_057069.1	FReD	288..501	CDD:238040	76/203 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2579
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X25
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.810