DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31832 and ANGPTL4

DIOPT Version :9

Sequence 1:	NP_723894.2	Gene:	CG31832 / 318970	FlyBaseID:	FBgn0051832	Length:	227	Species:	Drosophila melanogaster
Sequence 2:	XP_005272541.1	Gene:	ANGPTL4 / 51129	HGNCID:	16039	Length:	424	Species:	Homo sapiens

Alignment Length:	241	Identity:	82/241 - (34%)
Similarity:	118/241 - (48%)	Gaps:	44/241 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 LFEVGQSSP---HTCPSGSPNGIHQLMLPEEEPFQVTQCKTTA-RDWIVIQRRLDGSVNFNQSWF 74
            ||:||:...   ...|.|||            ||.| .||.|: ..|.|||||.||||:||:.|.
Human   191 LFQVGERQSGLFEIQPQGSP------------PFLV-NCKMTSDGGWTVIQRRHDGSVDFNRPWE 242

  Fly    75 SYKDGFGDPNGEFFIGLQKLYLMTREQPHELFIQLKHGPGATVYAHFDDFQVDSETELYKLERVG 139
            :||.|||||:|||::||:|::.:|.::...|.:||:...|......| ...:..|...|.|:...
Human   243 AYKAGFGDPHGEFWLGLEKVHSITGDRNSRLAVQLRDWDGNAELLQF-SVHLGGEDTAYSLQLTA 306

  Fly   140 KYSGTAGDSL--RYHINKRFSTFDRDND-ESSKNCA-----------AEH-------GGGWWFHS 183
            ..:|..|.:.  ...::..|||:|:|:| ...||||           .:|       .|||||.:
Human   307 PVAGQLGATTVPPSGLSVPFSTWDQDHDLRRDKNCAKSLSAPSVAQRPDHVPSPLTPAGGWWFGT 371

  Fly   184 CLSSSLNGLYFR---EGETGMLNGIHWGRW--KFQSLTFVQIMIRP 224
            |..|:|||.|||   :....:..||.|..|  ::..|....::|:|
Human   372 CSHSNLNGQYFRSIPQQRQKLKKGIFWKTWRGRYYPLQATTMLIQP 417

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31832	NP_723894.2	FReD	28..225	CDD:238040	77/224 (34%)
ANGPTL4	XP_005272541.1	FReD	183..418	CDD:238040	82/241 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2579
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810