DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31832 and angptl2b

DIOPT Version :9

Sequence 1:	NP_723894.2	Gene:	CG31832 / 318970	FlyBaseID:	FBgn0051832	Length:	227	Species:	Drosophila melanogaster
Sequence 2:	NP_001119950.1	Gene:	angptl2b / 503514	ZFINID:	ZDB-GENE-050624-1	Length:	519	Species:	Danio rerio

Alignment Length:	228	Identity:	83/228 - (36%)
Similarity:	132/228 - (57%)	Gaps:	22/228 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 GQSSPHTC--PSG-------------SPNGIHQLMLPEEEPFQVTQC--KTTARDWIVIQRRLDG 65
            |..||.|.  |||             :.:|:|.:............|  :.....|.|||||:||
Zfish   287 GTHSPSTTNKPSGPWKDCLEALEDGHTNSGMHLVKPDNTNKLMQVWCDQRQDPGGWTVIQRRMDG 351

  Fly    66 SVNFNQSWFSYKDGFGDPNGEFFIGLQKLYLMTREQPHELFIQLKHGPGATVYAHFDDFQVDSET 130
            ||||.::|.:||.|||:.:||:::||:.:|.:|.:..::|.:.|:...|...:|.:..|:::.|.
Zfish   352 SVNFFRNWETYKQGFGNIDGEYWLGLENIYWITNQGNYKLLVTLEDWSGRKTFAEYASFRLEPEA 416

  Fly   131 ELYKLERVGKYSGTAGDSLRYHINKRFSTFDRDNDESSKNCAAEHGGGWWFHSCLSSSLNGLYFR 195
            :.|:| |||:|.|.|||||.:|..|:|:|.|||:|..:.|||....||||:::|..|:|||:::|
Zfish   417 DFYRL-RVGRYHGNAGDSLTWHNGKQFTTLDRDHDVYTGNCAHYQKGGWWYNACAHSNLNGVWYR 480

  Fly   196 EG--ETGMLNGIHWGRWK--FQSLTFVQIMIRP 224
            .|  .:...:|::|..::  ..||..|.:||||
Zfish   481 GGHYRSRYQDGVYWAEFRGGAYSLKKVVMMIRP 513

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31832	NP_723894.2	FReD	28..225	CDD:238040	77/216 (36%)
angptl2b	NP_001119950.1	RILP-like	98..216	CDD:304877
angptl2b	NP_001119950.1	FReD	299..513	CDD:238040	75/214 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2579
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X25
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.810