DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31832 and Tnn

DIOPT Version :9

Sequence 1:	NP_723894.2	Gene:	CG31832 / 318970	FlyBaseID:	FBgn0051832	Length:	227	Species:	Drosophila melanogaster
Sequence 2:	NP_808507.2	Gene:	Tnn / 329278	MGIID:	2665790	Length:	1560	Species:	Mus musculus

Alignment Length:	229	Identity:	93/229 - (40%)
Similarity:	125/229 - (54%)	Gaps:	23/229 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 TLLFEVGQSSPHTCPS---------GSPNGIHQLML--PEEEPFQV-TQCKTTARDWIVIQRRLD 64
            |.|..|....||  ||         .:.:|::.:.|  ....|.|| ....|....|||.|||..
Mouse  1317 TTLSTVDARFPH--PSDCSQVQQNTNAASGLYTIYLNGDASRPMQVYCDMDTDGGGWIVFQRRNT 1379

  Fly    65 GSVNFNQSWFSYKDGFGDPNGEFFIGLQKLYLMT--REQPHELFIQLKHGPGATVYAHFDDFQVD 127
            |.::|.:.|.||.:|||||..||::||.||:.:|  ....:|:...|:.. ..:.||.:|.|||.
Mouse  1380 GQLDFFKRWRSYVEGFGDPMKEFWLGLDKLHNLTTGTTTRYEVRADLQTF-NESAYAVYDFFQVA 1443

  Fly   128 SETELYKLERVGKYSGTAGDSLRYHINKRFSTFDRDNDESSKNCAAEHGGGWWFHSCLSSSLNGL 192
            |..|.|||. ||||.|||||:|.||...:|:|||||||.:..|||..|.||||:.:|..::.||.
Mouse  1444 SSKERYKLS-VGKYRGTAGDALTYHNGWKFTTFDRDNDIALSNCALTHHGGWWYKNCHLANPNGK 1507

  Fly   193 YFREGETGMLNGIHWGRWKFQ--SLTFVQIMIRP 224
            |   |||....|::|..||..  |:.:|::.|||
Mouse  1508 Y---GETKHSEGVNWEPWKGHEFSIPYVELKIRP 1538

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31832	NP_723894.2	FReD	28..225	CDD:238040	86/204 (42%)
Tnn	NP_808507.2	EGF_2	<142..166	CDD:285248
		EGF_2	169..197	CDD:285248
		EB	181..233	CDD:279949
		EGF_2	233..259	CDD:285248
		fn3	264..332	CDD:278470
		fn3	359..434	CDD:278470
		fn3	444..521	CDD:278470
		FN3	532..608	CDD:214495
		FN3	620..696	CDD:214495
		fn3	708..785	CDD:278470
		fn3	796..875	CDD:278470
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	868..888
		fn3	884..961	CDD:278470
		fn3	972..1049	CDD:278470
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1044..1063
		FN3	1060..1136	CDD:214495
		fn3	1148..1225	CDD:278470
		fn3	1236..1313	CDD:278470
		FReD	1327..1539	CDD:238040	90/219 (41%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2579
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810