DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG31832 and ANGPTL3

DIOPT Version :9

Sequence 1:NP_723894.2 Gene:CG31832 / 318970 FlyBaseID:FBgn0051832 Length:227 Species:Drosophila melanogaster
Sequence 2:NP_055310.1 Gene:ANGPTL3 / 27329 HGNCID:491 Length:460 Species:Homo sapiens


Alignment Length:221 Identity:63/221 - (28%)
Similarity:111/221 - (50%) Gaps:22/221 - (9%)


- Green bases have known domain annotations that are detailed below.


  Fly    12 TLLFEVGQSSPHTCPSGSPNGIHQLMLPEEEPFQVTQCKTTARDWIVIQRRLDGSVNFNQSWFSY 76
            |.::..|:   ||      :|::.:.....:.|.|.....:...|.:||.|:|||.|||::|.:|
Human   247 TTIYNRGE---HT------SGMYAIRPSNSQVFHVYCDVISGSPWTLIQHRIDGSQNFNETWENY 302

  Fly    77 KDGFGDPNGEFFIGLQKLYLMTREQPHELFIQLKHGPGATVYAHFDDFQVDSETELYKLERVGKY 141
            |.|||..:|||::||:|:|.:.::..:.|.|:|:.......|..:..:..:.||. |.|..|. .
Human   303 KYGFGRLDGEFWLGLEKIYSIVKQSNYVLRIELEDWKDNKHYIEYSFYLGNHETN-YTLHLVA-I 365

  Fly   142 SGTAGDSLRYHINKRFSTFDRDNDESSKNCAAEHGGGWWFH-SCLSSSLNGLYFR---EGETGML 202
            :|...:::..:.:..|||:|. ..:...||...:.||||:| .|..::|||.|.:   :.:....
Human   366 TGNVPNAIPENKDLVFSTWDH-KAKGHFNCPEGYSGGWWWHDECGENNLNGKYNKPRAKSKPERR 429

  Fly   203 NGIHW----GRWKFQSLTFVQIMIRP 224
            .|:.|    ||  ..|:...:::|.|
Human   430 RGLSWKSQNGR--LYSIKSTKMLIHP 453

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG31832NP_723894.2 FReD 28..225 CDD:238040 59/205 (29%)
ANGPTL3NP_055310.1 SMC_N <84..>215 CDD:330553
FReD 243..453 CDD:238040 62/219 (28%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG2579
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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