DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG31832 and FCN1

DIOPT Version :9

Sequence 1:NP_723894.2 Gene:CG31832 / 318970 FlyBaseID:FBgn0051832 Length:227 Species:Drosophila melanogaster
Sequence 2:NP_001994.2 Gene:FCN1 / 2219 HGNCID:3623 Length:326 Species:Homo sapiens


Alignment Length:224 Identity:82/224 - (36%)
Similarity:114/224 - (50%) Gaps:17/224 - (7%)


- Green bases have known domain annotations that are detailed below.


  Fly    16 EVGQSSPHTCPSGSPN------------GIHQLMLPEEEPFQV-TQCKTTARDWIVIQRRLDGSV 67
            :.|||  .:|.:|..|            |.|.:.||:..|..| ....|....|.|.|||:||||
Human   104 DAGQS--QSCATGPRNCKDLLDRGYFLSGWHTIYLPDCRPLTVLCDMDTDGGGWTVFQRRMDGSV 166

  Fly    68 NFNQSWFSYKDGFGDPNGEFFIGLQKLYLMTREQPHELFIQLKHGPGATVYAHFDDFQVDSETEL 132
            :|.:.|.:||.|||...|||::|...::.:|.:...||.:.|....|...:|.:..|:|..|.|.
Human   167 DFYRDWAAYKQGFGSQLGEFWLGNDNIHALTAQGSSELRVDLVDFEGNHQFAKYKSFKVADEAEK 231

  Fly   133 YKLERVGKYSGTAGDSLRYHINKRFSTFDRDNDESSKNCAAEHGGGWWFHSCLSSSLNGLYFREG 197
            |||.......|:||:||..|.|..|||.|:|||.||.|||.:..|.||:..|.:|:|||||....
Human   232 YKLVLGAFVGGSAGNSLTGHNNNFFSTKDQDNDVSSSNCAEKFQGAWWYADCHASNLNGLYLMGP 296

  Fly   198 ETGMLNGIHWGRWKFQSLTF--VQIMIRP 224
            .....|||:|...|....::  .::.:||
Human   297 HESYANGINWSAAKGYKYSYKVSEMKVRP 325

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG31832NP_723894.2 FReD 28..225 CDD:238040 78/212 (37%)
FCN1NP_001994.2 Collagen 51..107 CDD:189968 0/2 (0%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 72..111 3/8 (38%)
FReD 115..325 CDD:238040 75/209 (36%)
A domain, contributes to trimerization 115..154 8/38 (21%)
B domain, contributes to trimerization 155..243 33/87 (38%)
Carbohydrate-binding. /evidence=ECO:0000269|PubMed:17897951 282..284 0/1 (0%)
P domain. /evidence=ECO:0000303|PubMed:17148457 317..326 2/9 (22%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG2579
Hieranoid 1 1.000 - -
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0000029
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X25
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
54.810

Return to query results.
Submit another query.