DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31832 and Angpt2

DIOPT Version :9

Sequence 1:	NP_723894.2	Gene:	CG31832 / 318970	FlyBaseID:	FBgn0051832	Length:	227	Species:	Drosophila melanogaster
Sequence 2:	NP_031452.2	Gene:	Angpt2 / 11601	MGIID:	1202890	Length:	496	Species:	Mus musculus

Alignment Length:	203	Identity:	76/203 - (37%)
Similarity:	105/203 - (51%)	Gaps:	7/203 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 NGIHQLMLPE--EEPFQVTQCKTTARDWIVIQRRLDGSVNFNQSWFSYKDGFGDPNGEFFIGLQK 93
            :||:.|..|.  ||.............|.|||.|.||||:|.::|..||:|||.|.||:::|.:.
Mouse   295 SGIYTLTFPNSTEEIKAYCDMDVGGGGWTVIQHREDGSVDFQRTWKEYKEGFGSPLGEYWLGNEF 359

  Fly    94 LYLMTREQPHELFIQLKHGPGATVYAHFDDFQVDSETELYKLERVGKYSGTAGD-SLRYHINKRF 157
            :..:|.:..:.|.||||...|...::.:|.|.:..|...|::...| .:||||. |........|
Mouse   360 VSQLTGQHRYVLKIQLKDWEGNEAHSLYDHFYLAGEESNYRIHLTG-LTGTAGKISSISQPGSDF 423

  Fly   158 STFDRDNDESSKNCAAEHGGGWWFHSCLSSSLNGLYF-REGETGMLNGIHWGRWKFQ--SLTFVQ 219
            ||.|.|||:....|:....|||||.:|..|:|||.|: ::..|...|||.|..||..  ||....
Mouse   424 STKDSDNDKCICKCSQMLSGGWWFDACGPSNLNGQYYPQKQNTNKFNGIKWYYWKGSGYSLKATT 488

  Fly   220 IMIRPKYF 227
            :||||..|
Mouse   489 MMIRPADF 496

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31832	NP_723894.2	FReD	28..225	CDD:238040	74/199 (37%)
Angpt2	NP_031452.2	RILP-like	<168..226	CDD:304877
Angpt2	NP_031452.2	FBG	280..494	CDD:214548	74/199 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2579
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X25
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.900